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Collaboration, Licensing and Other Arrangements - Additional Information (Detail) - USD ($) | 1 Months Ended | 3 Months Ended | 12 Months Ended |
--- | --- | --- | --- | ---
Dec. 31, 2022 | May 31, 2018 | Mar. 31, 2023 | Mar. 31, 2022 | Dec. 31, 2022 | Feb. 28, 2023
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |
Deferred revenue - current |  | $ 1,733,000 |  | $ 2,316,000 |  | $ 1,733,000 |
Deferred revenue - non-current |  | 37,684,000 |  | 45,659,000 |  | 37,684,000 |
Total revenue from UT |  |  |  | 40,626,000 | $ 11,992,000 |  |
Collaborations and services |  |  |  |  |  |  |
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |
Total revenue from UT |  |  |  | 11,386,000 | 2,166,000 |  |
AFREZZA product sales |  |  |  |  |  |  |
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |
Total revenue from UT |  |  |  | 17,562,000 | 9,826,000 |  |
United Therapeutics Corporation |  |  |  |  |  |  |
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |
Total revenue from UT |  |  |  | 23,027,000 | 2,042,000 |  |
United Therapeutics Corporation | Manufacturing Services |  |  |  |  |  |  |
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |
Funding for development of alternative manufacturing processes |  | 2,300,000 |  |  |  |  |
United Therapeutics Corporation | Commercialization and Continuous Improvement Activities |  |  |  |  |  |  |
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |
Funding for capital improvements |  | 39,500,000 |  |  |  |  |
Thirona Bio, Inc. |  |  |  |  |  |  |
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |
Minimum amount to expended |  |  |  |  |  |  | $ 1,100,000
Collaboration and License Agreement | United Therapeutics Corporation |  |  |  |  |  |  |
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |
Total anticipated cash flows | [1] | 722,300,000 |  |  |  | 722,300,000 |
Deferred revenue |  | 37,900,000 |  | 46,500,000 |  | 37,900,000 |
Deferred revenue - current |  | 1,600,000 |  | 2,200,000 |  | 1,600,000 |
Deferred revenue - non-current |  | 36,300,000 |  | 44,300,000 |  | 36,300,000 |
Collaboration and License Agreement | United Therapeutics Corporation | Manufacturing Services |  |  |  |  |  |  |
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |
Total anticipated cash flows |  | 722,300,000 |  |  |  | 722,300,000 |
Allocated transaction price |  | 220,800,000 |  |  |  |  |
Collaboration and License Agreement | United Therapeutics Corporation | Manufacturing Services | Transaction Price For The Contractual Obligations |  |  |  |  |  |  |
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |
Total anticipated cash flows |  | 120,000,000.0 |  |  |  | 120,000,000.0 |
Collaboration and License Agreement | United Therapeutics Corporation | Next-Gen R&D Services | Transaction Price For The Performance Obligations |  |  |  |  |  |  |
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |
Total anticipated cash flows |  | $ 602,300,000 |  |  |  | 602,300,000 |
Commercial Supply Agreement | United Therapeutics Corporation |  |  |  |  |  |  |
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |
Total revenue from UT |  |  |  | 11,164,000 | 694,000 |  |
Supply and Distribution Agreement | AFREZZA product sales | Biomm |  |  |  |  |  |  |
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |
Total revenue from UT |  |  |  | 0 |  | $ 0 |
License and Distribution Agreement | Cipla Ltd |  |  |  |  |  |  |
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |
Deferred revenue |  |  |  | 1,500,000 |  |  |
Deferred revenue - current |  |  |  | 200,000 |  |  |
Deferred revenue - non-current |  |  |  | 1,300,000 |  |  |
Marketing and distribution agreement date |  |  | 2018-05 |  |  |  |
License and Distribution Agreement | Collaborations and services | Cipla Ltd |  |  |  |  |  |  |
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |
Total revenue from UT |  |  |  | $ 37,000 | $ 37,000 |  |
[1] | The total anticipated cash flow includes a transaction price of $120.0 million for the contractual obligations under the CSA for the Manufacturing Services and the Next-Gen R&D Services performance obligations and $602.3 million for future supply of Tyvaso DPI over the remaining term of the CSA.

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