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v3.23.1

Description of Business and Significant Accounting Policies - Additional Information (Detail) | 1 Months Ended | 3 Months Ended |  |  |
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Jan. 31, 2022 USD ($) | Jun. 30, 2021 USD ($) | Apr. 30, 2021 USD ($) | Mar. 31, 2023 USD ($) Segment | Mar. 31, 2022 USD ($) | Dec. 31, 2022 USD ($) | Mar. 31, 2021 USD ($) | Jul. 01, 2013 USD ($)
Organization Consolidation And Presentation Of Financial Statements Disclosure [Line Items] |  |  |  |  |  |  |  |  |
Accumulated deficit |  |  |  |  | $ (3,227,264,000) |  | $ (3,217,469,000) |  |
Cash and cash equivalents |  |  |  |  | 85,869,000 |  | 69,767,000 |  |
Short-term investments |  |  |  |  | 80,273,000 |  | 101,079,000 |  |
Long-term investments |  |  |  |  | 492,000 |  | 1,961,000 |  |
Financing liability |  |  |  |  | $ 104,000,000.0 |  | 104,100,000 |  |
Number of operating segment | Segment |  |  |  |  | 1 |  |  |  |
Purchase of available-for-sale investment |  |  |  |  |  | $ 5,000,000 |  |  |
Maximum | AFREZZA product sales |  |  |  |  |  |  |  |  |
Organization Consolidation And Presentation Of Financial Statements Disclosure [Line Items] |  |  |  |  |  |  |  |  |
Sales return right following product expiration in months |  |  |  |  | 12 months |  |  |  |
Minimum | AFREZZA product sales |  |  |  |  |  |  |  |  |
Organization Consolidation And Presentation Of Financial Statements Disclosure [Line Items] |  |  |  |  |  |  |  |  |
Sales return right following product expiration in months |  |  |  |  | 6 months |  |  |  |
Convertible Promissory Note | Thirona Bio, Inc. |  |  |  |  |  |  |  |  |
Organization Consolidation And Presentation Of Financial Statements Disclosure [Line Items] |  |  |  |  |  |  |  |  |
Purchase of available-for-sale investment |  | $ 5,000,000.0 | $ 3,000,000.0 |  |  |  |  |  |
Interest rate |  |  |  |  | 6.00% |  |  |  |
MidCap Credit Facility |  |  |  |  |  |  |  |  |
Organization Consolidation And Presentation Of Financial Statements Disclosure [Line Items] |  |  |  |  |  |  |  |  |
Principal amount | [1] |  |  |  | $ 40,000,000.0 |  | $ 40,000,000.0 |  |
Principal prepayment against outstanding term loans |  |  |  | $ 10,000,000.0 |  |  |  |  |
MidCap Credit Facility | Tranche Three |  |  |  |  |  |  |  |  |
Organization Consolidation And Presentation Of Financial Statements Disclosure [Line Items] |  |  |  |  |  |  |  |  |
Amount available under credit facility |  |  |  | $ 60,000,000.0 | 60,000,000.0 |  |  | $ 25,000,000.0 |
Milestone Rights Liability | Deerfield |  |  |  |  |  |  |  |  |
Organization Consolidation And Presentation Of Financial Statements Disclosure [Line Items] |  |  |  |  |  |  |  |  |
Contingent liability remain payable |  |  |  |  | $ 60,000,000.0 |  |  |  | $ 60,000,000.0
Milestone Rights Liability | Maximum | Deerfield |  |  |  |  |  |  |  |  |
Organization Consolidation And Presentation Of Financial Statements Disclosure [Line Items] |  |  |  |  |  |  |  |  |
Contingent liability for milestone payments |  |  |  |  |  |  |  |  | $ 90,000,000.0
[1] | In August 2022, the Company amended the MidCap credit facility and transitioned the benchmark interest rate from LIBOR to the Secured Overnight Financing Rate (“SOFR”). The interest rate prior to the amendment was one-month LIBOR (1% floor) plus 6.25% (capped at a total of 8.25%).

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