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Collaboration, Licensing and Other Arrangements - Schedule of Revised Anticipated Cash Flows from Transactions Allocated Performance Obligations (Parenthetical) (Detail) - United Therapeutics Corporation - Collaboration and License Agreement $ in Millions | 1 Months Ended
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Dec. 31, 2022 USD ($)
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |
Total anticipated cash flows | $ 722.3 | [1]
Manufacturing Services |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |
Total anticipated cash flows | 722.3 |
Allocated transaction price | 220.8 |
Manufacturing Services | Transaction Price For The Contractual Obligations |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |
Total anticipated cash flows | 120.0 |
Next-Gen R&D Services | Transaction Price For The Performance Obligations |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |
Total anticipated cash flows | $ 602.3 |
[1] | The total anticipated cash flow includes a transaction price of $120.0 million for the contractual obligations under the CSA for the Manufacturing Services and the Next-Gen R&D Services performance obligations and $602.3 million for future supply of Tyvaso DPI over the remaining term of the CSA.

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