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Collaboration, Licensing and Other Arrangements - Schedule of Revised Anticipated Cash Flows from Transactions Allocated Performance Obligations (Detail) - Collaboration and License Agreement - United Therapeutics Corporation $ in Millions | 1 Months Ended
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Dec. 31, 2022 USD ($)
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |  |
Total anticipated cash flows | $ 722.3 | [1]
R&D Services and License | Over Time |  |
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |  |
Progress Measure | Ratably |
Recognition Period | Aug 2021 - Oct 2021 |
Next-Gen R&D Services | Over Time |  |
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |  |
Anticipated Revenue Allocation | $ 10.0 |
Progress Measure | Input |
Recognition Period | % of completion of costs |
Manufacturing Services and Product Sales | Point In Time |  |
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |  |
Anticipated Revenue Allocation | $ 712.3 | [2]
Recognition Period | Transfer of control | [2]
Manufacturing Services |  |
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |  |
Total anticipated cash flows | $ 722.3 |
[1] | The total anticipated cash flow includes a transaction price of $120.0 million for the contractual obligations under the CSA for the Manufacturing Services and the Next-Gen R&D Services performance obligations and $602.3 million for future supply of Tyvaso DPI over the remaining term of the CSA.
[2] | The Manufacturing Services performance obligation will be recognized as control of manufactured products is transferred to UT. The modification did not result in a cumulative catch-up adjustment as a result of the revenue being deferred for the performance obligations that were affected by the modification. The allocation of the transaction price for the Manufacturing Services includes a material right related to the Company’s estimated production of product in the amount of $220.8 million. The Company will sell product to UT under individual purchase orders, which represent distinct performance obligations. The ultimate cash flows may vary as manufacturing purchase orders are received.

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