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Accounts Receivable - Additional Information (Detail)	12 Months Ended
	Dec. 31, 2023 USD ($) Distributor	Dec. 31, 2022 USD ($) Distributor
Accounts Receivable [Line Items]
Number of wholesale distributors | Distributor	3	3
Percentage of gross sales from major wholesale distributors	85.00%	74.00%
Allowance for credit losses and doubtful accounts	$ 0
Percentage of revenue from major customers collaborations and services	100.00%	98.00%
United Therapeutics Corporation
Accounts Receivable [Line Items]
Percentage of collaborations and services net accounts receivables	100.00%
Zealand
Accounts Receivable [Line Items]
Allowance for credit losses and doubtful accounts	$ 200,000
Accounts receivable	$ 200,000
Commercial product sales
Accounts Receivable [Line Items]
Percentage of accounts receivable from major wholesale distributors	74.00%	79.00%
Allowance for credit losses and doubtful accounts	$ 157,000
Accounts receivable	$ 20,199,000	$ 19,359,000

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Amount, before allowance for credit loss, of right to consideration from customer for product sold and service rendered in normal course of business, classified as current.

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Reference 1: http://www.xbrl.org/2003/role/disclosureRef
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