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Description of Business and Significant Accounting Policies - Additional Information (Detail) € in Millions | 1 Months Ended | 3 Months Ended |  |  |  |
--- | --- | --- | --- | --- | --- | ---
Jan. 31, 2022 USD ($) | Jun. 30, 2021 USD ($) | Apr. 30, 2021 USD ($) | Mar. 31, 2024 USD ($) Segment | Mar. 31, 2024 EUR (€) | Dec. 31, 2023 USD ($) | Aug. 31, 2019 USD ($) | Jul. 01, 2013 USD ($)
Organization Consolidation And Presentation Of Financial Statements Disclosure [Line Items] |  |  |  |  |  |  |  |
Accumulated deficit |  |  |  | $ (3,218,777,000) |  | $ (3,229,407,000) |  |
Cash and cash equivalents |  |  |  | 193,272,000 |  | 238,480,000 |  |
Short-term investments |  |  |  | 107,457,000 |  | 56,619,000 |  |
Long-term investments |  |  |  | 3,726,000 |  | 7,155,000 |  |
Financing liability |  |  |  | $ 104,100,000 |  | 104,100,000 |  |
Percentage of future royalties |  |  |  | 1.00% |  |  |  |
Number of operating segment | Segment |  |  |  | 1 |  |  |  |
Loss on purchase commitments | € |  |  |  |  | € 58.9 |  |  |
Insulin |  |  |  |  |  |  |  |
Organization Consolidation And Presentation Of Financial Statements Disclosure [Line Items] |  |  |  |  |  |  |  |
Loss on purchase commitments |  |  |  | $ 62,700,000 |  | 64,800,000 |  |
Tyvaso DPI |  |  |  |  |  |  |  |
Organization Consolidation And Presentation Of Financial Statements Disclosure [Line Items] |  |  |  |  |  |  |  |
Percentage of royalty on net sales |  |  |  | 10.00% |  |  |  |
Percentage of royalty on net revenue |  |  |  | 10.00% |  |  |  |
Percentage of future royalties |  |  |  | 9.00% |  |  |  |
Maximum | AFREZZA product sales |  |  |  |  |  |  |  |
Organization Consolidation And Presentation Of Financial Statements Disclosure [Line Items] |  |  |  |  |  |  |  |
Sales return right following product expiration in months |  |  |  | 12 months |  |  |  |
Minimum | AFREZZA product sales |  |  |  |  |  |  |  |
Organization Consolidation And Presentation Of Financial Statements Disclosure [Line Items] |  |  |  |  |  |  |  |
Sales return right following product expiration in months |  |  |  | 6 months |  |  |  |
Convertible Promissory Note | Thirona Bio, Inc. |  |  |  |  |  |  |  |
Organization Consolidation And Presentation Of Financial Statements Disclosure [Line Items] |  |  |  |  |  |  |  |
Principal amount |  |  |  | $ 8,000,000 |  |  |  |
Purchase of available-for-sale securities | $ 5,000,000.0 | $ 3,000,000 |  |  |  |  |  |
Interest rate |  | 6.00% |  |  |  |  |  |
MidCap Credit Facility |  |  |  |  |  |  |  |
Organization Consolidation And Presentation Of Financial Statements Disclosure [Line Items] |  |  |  |  |  |  |  |
Principal amount |  |  |  | $ 28,300,000 |  | $ 33,300,000 |  |
Principal prepayment against outstanding term loans |  |  | $ 10,000,000.0 |  |  |  |  |
MidCap Credit Facility | Tranche Three |  |  |  |  |  |  |  |
Organization Consolidation And Presentation Of Financial Statements Disclosure [Line Items] |  |  |  |  |  |  |  |
Amount available under credit facility |  |  |  |  |  |  | $ 60,000,000 |
Milestone Rights Liability | Deerfield |  |  |  |  |  |  |  |
Organization Consolidation And Presentation Of Financial Statements Disclosure [Line Items] |  |  |  |  |  |  |  |
Contingent liability remain payable |  |  |  |  |  |  |  | $ 55,000,000
Milestone Rights Liability | Maximum | Deerfield |  |  |  |  |  |  |  |
Organization Consolidation And Presentation Of Financial Statements Disclosure [Line Items] |  |  |  |  |  |  |  |
Contingent liability for milestone payments |  |  |  |  |  |  |  | $ 90,000,000

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