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Note 6 - Share-based Compensation - Summary of Stock Option Activity (Details) - Employee and Nonemployee Stock Option [Member]
$ / shares in Units, $ in Thousands
9 Months Ended
Sep. 30, 2021
USD ($)
$ / shares
shares
Outstanding, shares under options (in shares) | shares 94,513
Outstanding, weighted average exercise price (in dollars per share) | $ / shares $ 30.22
Share-based Compensation Arrangement by Share-based Payment Award, Options, Grants in Period, Gross (in shares) | shares 10,716
Granted (in dollars per share) | $ / shares $ 57.34
Exercised, shares under options (in shares) | shares (6,558)
Granted, weighted average exercise price (in dollars per share) | $ / shares $ 24.77
Outstanding, shares under options (in shares) | shares 98,671
Outstanding, weighted average exercise price (in dollars per share) | $ / shares $ 33.53
Outstanding, weighted average remaining contractual life (Year) 6 years 21 days
Outstanding, aggregate intrinsic value | $ $ 2,769
Exercisable, shares under options (in shares) | shares 87,955
Exercisable, weighted average exercise price (in dollars per share) | $ / shares $ 30.63
Exercisable, weighted average remaining contractual life (Year) 5 years 7 months 13 days
Exercisable, aggregate intrinsic value | $ $ 2,723
Vested and expected to vest, shares under options (in shares) | shares 98,671
Vested and expected to vest, weighted average exercise price (in dollars per share) | $ / shares $ 33.53
Vested and expected to vest, weighted average remaining contractual life (Year) 6 years 21 days
Vested and expected to vest, aggregate intrinsic value | $ $ 2,769