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Note 7 - Share-based Compensation - Summary of Stock Option Activity (Details) - Employee and Nonemployee Stock Option [Member]
$ / shares in Units, $ in Thousands
 3 Months Ended 6 Months Ended
Mar. 31, 2023
$ / shares
shares
Jun. 30, 2023
USD ($)
$ / shares
shares
Outstanding, shares under options (in shares) | shares 92,075 92,075
Outstanding, weighted average exercise price (in dollars per share) | $ / shares $ 39.98 $ 39.98
Granted, shares under options (in shares) | shares   12,153
Granted (in dollars per share) | $ / shares   $ 131.13
Exercised, shares under options (in shares) | shares   (25,740)
Granted, weighted average exercise price (in dollars per share) | $ / shares $ 30.67  
Outstanding, shares under options (in shares) | shares   78,488
Outstanding, weighted average exercise price (in dollars per share) | $ / shares   $ 57.14
Outstanding, weighted average remaining contractual life (Year)   6 years 21 days
Outstanding, aggregate intrinsic value | $   $ 10,730
Exercisable, shares under options (in shares) | shares   66,335
Exercisable, weighted average exercise price (in dollars per share) | $ / shares   $ 43.59
Exercisable, weighted average remaining contractual life (Year)   5 years 11 months 23 days
Exercisable, aggregate intrinsic value | $   $ 9,967
Vested and expected to vest, shares under options (in shares) | shares   78,488
Vested and expected to vest, weighted average exercise price (in dollars per share) | $ / shares   $ 57.14
Vested and expected to vest, weighted average remaining contractual life (Year)   6 years 21 days
Vested and expected to vest, aggregate intrinsic value | $   $ 10,730