    <SEC-DOCUMENT>0000950123-21-004949-index.html : 20211216
    <SEC-HEADER>0000950123-21-004949.hdr.sgml : 20211216
    <ACCEPTANCE-DATETIME>20210426164517
    <PRIVATE-TO-PUBLIC>
    ACCESSION NUMBER:		0000950123-21-004949
    CONFORMED SUBMISSION TYPE:	DRS
    PUBLIC DOCUMENT COUNT:		8
    FILED AS OF DATE:		20210426
    <PUBLIC-REL-DATE>20211216
    DATE AS OF CHANGE:		20210427

    FILER:

    	COMPANY DATA:
    		COMPANY CONFORMED NAME:			Amylyx Pharmaceuticals, Inc.
    		CENTRAL INDEX KEY:			0001658551
    		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
    		IRS NUMBER:				464600503
    		STATE OF INCORPORATION:			DE
    		FISCAL YEAR END:			1231

    	FILING VALUES:
    		FORM TYPE:		DRS
    		SEC ACT:		1933 Act
    		SEC FILE NUMBER:	377-04729
    		FILM NUMBER:		21854475

    	BUSINESS ADDRESS:
    		STREET 1:		43 THORNDIKE STREET
    		CITY:			CAMBRIDGE
    		STATE:			MA
    		ZIP:			02141
    		BUSINESS PHONE:		617-683-0917

    	MAIL ADDRESS:
    		STREET 1:		43 THORNDIKE STREET
    		CITY:			CAMBRIDGE
    		STATE:			MA
    		ZIP:			02141
    </SEC-HEADER>
    <DOCUMENT>
    <TYPE>DRS
    <SEQUENCE>1
    <FILENAME>filename1.htm
    <TEXT>
    Document 1 - file: filename1.htm

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>2
    <FILENAME>g155225g11d11.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 2 - file: g155225g11d11.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>3
    <FILENAME>g155225g13a00.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 3 - file: g155225g13a00.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>4
    <FILENAME>g155225g22z92.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 4 - file: g155225g22z92.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>5
    <FILENAME>g155225g36n42.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 5 - file: g155225g36n42.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>6
    <FILENAME>g155225g80r72.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 6 - file: g155225g80r72.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>7
    <FILENAME>g155225g92x08.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 7 - file: g155225g92x08.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>8
    <FILENAME>g155225g93a99.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 8 - file: g155225g93a99.jpg

    </DOCUMENT>
    </SEC-DOCUMENT>