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CONDENSED CONSOLIDATED STATEMENTS OF CASH FLOWS - USD ($) $ in Thousands | 9 Months Ended
--- | ---
Sep. 30, 2022 | Sep. 30, 2021
Cash flows used in operating activities: |  |
Net loss | $ (155,671) | $ (59,587)
Adjustments to reconcile net loss to net cash used in operating activities: |  |
Stock-based compensation expense | 15,623 | 2,045
Depreciation expense | 305 | 30
Amortization (accretion) of investment premiums (discounts) | (196) | 23
Change in fair value of convertible notes |  | 5,228
Changes in operating assets and liabilities: |  |
Accounts receivable, net | (137) |
Inventories | (563) |
Interest receivable | (61) |
Prepaid expenses and other current assets | (2,879) | (1,764)
Operating lease right-of-use assets | 1,208 |
Other assets | (456) | 125
Accounts payable | 2,654 | (716)
Accrued expenses and deferred rent | 10,435 | 8,061
Operating lease liabilities | (436) |
Net cash used in operating activities | (130,174) | (46,555)
Cash flows used in investing activities: |  |
Purchases of property and equipment | (1,906) | (167)
Purchases of investments | (154,313) | (49,053)
Proceeds from maturities of short-term investments | 145,411 |
Net cash used in investing activities | (10,808) | (49,220)
Cash flows provided by financing activities: |  |
Proceeds from initial public offering | 200,897 |
Initial public offering costs paid | (1,518) |
Proceeds from issuance of convertible notes—related parties |  | 14,272
Proceeds from issuance of convertible notes |  | 11,887
Proceeds from issuance of Series C-1 redeemable convertible preferred stock, net of issuance costs |  | 134,791
Issuance costs related to conversion of convertible notes |  | (50)
Payment of deferred offering costs |  | (1,527)
Proceeds from exercise of stock options | 248 | 198
Net cash provided by financing activities | 199,627 | 159,571
Effect of exchange rate changes on cash, cash equivalents and restricted cash | (572) | 4
Net increase in cash, cash equivalents and restricted cash | 58,073 | 63,800
Cash, cash equivalents and restricted cash, beginning of period | 50,380 | 13,066
Cash, cash equivalents and restricted cash, end of period | 108,453 | 76,866
Supplemental disclosure of cash flow information: |  |
Unrealized loss on short-term investments | 165 | (5)
Purchases of property and equipment included in accounts payable | 43 | 41
Right-of-use assets and liabilities upon ASC842 adoption | 2,201 |
Right-of-use assets obtained in exchange for lease liabilities | 4,958 |
Movement of deferred offering costs to equity | 4,518 |
Initial public offering costs included in accounts payable and accrued expenses | 526 |
Public offering costs included in accounts payable and accrued expenses | 570 |
Deferred offering costs included in accounts payable and accrued expenses |  | 189
Conversion of convertible notes and accrued interest into redeemable convertible preferred stock |  | $ 32,548
Conversion of preferred stock to common stock upon initial public offering | 239,351 |
Income taxes paid | $ 27 |

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