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Income Taxes (Tables) | 12 Months Ended
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Dec. 31, 2022
Income Tax Disclosure [Abstract] |
Components of Net Loss Before Provision for Income Taxes | The components of net loss before the provision for income taxes are as follows:
|  | Year Ended December 31, |
|  | 2022 |  |  | 2021 |
|  | (in thousands) |
U.S. |  | $ | (198,704 | ) |  | $ | (87,904 | )
Non-U.S. |  |  | 1,103 |  |  |  | (27 | )
Loss before income taxes |  | $ | (197,601 | ) |  | $ | (87,931 | )
Schedule of Provision For Income Taxes | The provision for income taxes for the years ended December 31, 2022 and 2021 is as follows:
|  | Year Ended December 31, |
|  | 2022 |  |  | 2021 |
|  | (in thousands) |
Current income tax provision |  |  |  |  |  |
U.S. - Federal |  | $ | — |  |  | $ | — |
U.S. - State |  |  | — |  |  |  | — |
Non-U.S. |  |  | 774 |  |  |  | — |
Provision for income taxes |  | $ | 774 |  |  | $ | — |
Summary of Reconciliation of Effective Income Tax Rate to U.S. Statutory Federal Income Tax Rate | A reconciliation of the Company’s effective income tax rate to the U.S. statutory federal income tax rate of 21% for the years ended December 31, 2022 and 2021 is as follows:
|  | Year Ended December 31, |
|  | 2022 |  |  | 2021 |
Tax at U.S. statutory tax rate |  |  | 21.0 | % |  |  | 21.0 | %
State income tax benefit |  |  | 3.9 | % |  |  | 4.0 | %
Research and development tax credits |  |  | 1.4 | % |  |  | 1.5 | %
Valuation allowances |  |  | (25.5 | )% |  |  | (24.4 | )%
Other |  |  | (1.2 | )% |  |  | (2.1 | )%
Effective income tax rate |  |  | (0.4 | )% |  |  | 0.0 | %
Summary of Significant Components of Deferred Tax Assets and Liabilities | Significant components of the Company’s deferred tax assets and liabilities were as follows for the years ended December 31, 2022 and 2021:
|  | Year Ended December 31, |
|  | 2022 |  |  | 2021 |
|  | (in thousands) |
Deferred tax assets: |  |  |  |  |  |
Federal net operating loss carryforwards |  | $ | 42,673 |  |  | $ | 24,303 |
State net operating loss carryforwards |  |  | 10,628 |  |  |  | 5,474 |
Capitalized research and development costs |  |  | 18,079 |  |  |  | 6,205 |
Inventory |  |  | 5,721 |  |  |  | — |
Tax credits |  |  | 5,581 |  |  |  | 2,808 |
Accruals and other |  |  | 9,284 |  |  |  | 1,556 |
Total deferred tax assets |  | $ | 91,966 |  |  | $ | 40,346 |
Valuation allowance |  |  | (90,587 | ) |  |  | (40,346 | )
Net total deferred tax assets |  | $ | 1,379 |  |  | $ | — |
Deferred tax liabilities: |  |  |  |  |  |
Other |  |  | (1,379 | ) |  |  | — |
Total deferred tax liabilities |  | $ | (1,379 | ) |  | $ | — |
Net deferred tax assets |  | $ | — |  |  | $ | — |
Summary of Valuation Allowance | The following table reflects the roll-forward of the Company’s valuation allowance:
|  | Year Ended December 31, |
|  | 2022 |  |  | 2021 |
|  | (in thousands) |
Valuation allowance at beginning of year |  | $ | 40,346 |  |  | $ | 18,900 |
Increases recorded to income tax provision |  |  | 50,241 |  |  |  | 21,446 |
Valuation allowance at end of year |  | $ | 90,587 |  |  | $ | 40,346 |
Summary of Unrecognized Tax Benefits | A reconciliation of the beginning and ending amount of gross unrecognized tax benefits for the years ended December 31, 2022 and 2021 is as follows:
|  | Year Ended December 31, |
|  | 2022 |  |  | 2021 |
|  | (in thousands) |
Balance at beginning of the period |  | $ | 564 |  |  | $ | 349 |
Increases (decreases) related to tax positions taken during prior years |  |  | (32 | ) |  |  | — |
Increases related to tax positions taken during the prior years |  |  | 481 |  |  |  | 215 |
Balance at end of the period |  | $ | 1,013 |  |  | $ | 564 |

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