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Accrued Expenses - Schedule of Accrued Expenses (Details) - USD ($) $ in Thousands | Dec. 31, 2022 | Dec. 31, 2021
--- | --- | ---
Payables and Accruals [Abstract] |  |
External research and development | $ 8,424 | $ 5,666
Payroll and employee related expenses | 15,231 | 4,280
Manufacturing | 4,596 |
Accrued consulting and other professional fees | 4,116 | 2,820
Rebates and other GTN adjustments | 3,582 |
Royalty payable | 1,358 |
Other accrued expenses | 1,005 | 258
Total accrued expenses | $ 38,312 | $ 13,024

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