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Income Taxes (Tables)
12 Months Ended
Dec. 31, 2022
Income Tax Disclosure [Abstract]  
Components of Net Loss Before Provision for Income Taxes

The components of net loss before the provision for income taxes are as follows:

 

 

 

Year Ended
December 31,

 

 

 

2022

 

 

2021

 

 

 

(in thousands)

 

U.S.

 

$

(198,704

)

 

$

(87,904

)

Non-U.S.

 

 

1,103

 

 

 

(27

)

Loss before income taxes

 

$

(197,601

)

 

$

(87,931

)

Schedule of Provision For Income Taxes

The provision for income taxes for the years ended December 31, 2022 and 2021 is as follows:

 

 

 

Year Ended
December 31,

 

 

 

2022

 

 

2021

 

 

 

(in thousands)

 

Current income tax provision

 

 

 

 

 

 

U.S. - Federal

 

$

 

 

$

 

U.S. - State

 

 

 

 

 

 

Non-U.S.

 

 

774

 

 

 

 

Provision for income taxes

 

$

774

 

 

$

 

 

Summary of Reconciliation of Effective Income Tax Rate to U.S. Statutory Federal Income Tax Rate

A reconciliation of the Company’s effective income tax rate to the U.S. statutory federal income tax rate of 21% for the years ended December 31, 2022 and 2021 is as follows:

 

 

 

Year Ended
December 31,

 

 

 

2022

 

 

2021

 

Tax at U.S. statutory tax rate

 

 

21.0

%

 

 

21.0

%

State income tax benefit

 

 

3.9

%

 

 

4.0

%

Research and development tax credits

 

 

1.4

%

 

 

1.5

%

Valuation allowances

 

 

(25.5

)%

 

 

(24.4

)%

Other

 

 

(1.2

)%

 

 

(2.1

)%

Effective income tax rate

 

 

(0.4

)%

 

 

0.0

%

Summary of Significant Components of Deferred Tax Assets and Liabilities Significant components of the Company’s deferred tax assets and liabilities were as follows for the years ended December 31, 2022 and 2021:

 

 

 

Year Ended
December 31,

 

 

 

2022

 

 

2021

 

 

 

(in thousands)

 

Deferred tax assets:

 

 

 

 

 

 

Federal net operating loss carryforwards

 

$

42,673

 

 

$

24,303

 

State net operating loss carryforwards

 

 

10,628

 

 

 

5,474

 

Capitalized research and development costs

 

 

18,079

 

 

 

6,205

 

Inventory

 

 

5,721

 

 

 

 

Tax credits

 

 

5,581

 

 

 

2,808

 

Accruals and other

 

 

9,284

 

 

 

1,556

 

Total deferred tax assets

 

$

91,966

 

 

$

40,346

 

Valuation allowance

 

 

(90,587

)

 

 

(40,346

)

Net total deferred tax assets

 

$

1,379

 

 

$

 

Deferred tax liabilities:

 

 

 

 

 

 

Other

 

 

(1,379

)

 

 

 

Total deferred tax liabilities

 

$

(1,379

)

 

$

 

Net deferred tax assets

 

$

 

 

$

 

Summary of Valuation Allowance

The following table reflects the roll-forward of the Company’s valuation allowance:

 

 

 

Year Ended
December 31,

 

 

 

2022

 

 

2021

 

 

 

(in thousands)

 

Valuation allowance at beginning of year

 

$

40,346

 

 

$

18,900

 

Increases recorded to income tax provision

 

 

50,241

 

 

 

21,446

 

Valuation allowance at end of year

 

$

90,587

 

 

$

40,346

 

Summary of Unrecognized Tax Benefits A reconciliation of the beginning and ending amount of gross unrecognized tax benefits for the years ended December 31, 2022 and 2021 is as follows:

 

 

 

Year Ended
December 31,

 

 

 

2022

 

 

2021

 

 

 

(in thousands)

 

Balance at beginning of the period

 

$

564

 

 

$

349

 

Increases (decreases) related to tax positions taken during prior years

 

 

(32

)

 

 

 

Increases related to tax positions taken during the prior years

 

 

481

 

 

 

215

 

Balance at end of the period

 

$

1,013

 

 

$

564