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Note 1 - Significant Accounting Policies (Tables)

9 Months Ended

Sep. 30, 2015

Available-for-sale Securities [Table Text Block]

	September 30, 2015
	Amortized Cost		Accrued Interest		Gross Unrealized Gains		Gross Unrealized Losses			Estimated Fair Value
Obligations of U.S. Government and its agencies	$	23,119	$	42	$	28	$	(2	)	$	23,187
Corporate debt securities		27,249		141		26		(14	)		27,402
Certificates of deposit		20,909		28		10		(49	)		20,898

Total investments	$	71,277	$	211	$	64	$	(65	)	$	71,487

	December 31, 2014
	Amortized Cost		Accrued Interest		Gross Unrealized Gains		Gross Unrealized Losses			Estimated Fair Value
Obligations of U.S. Government and its agencies	$	20,307	$	22	$	—	$	(23	)	$	20,306
Corporate debt securities		27,152		151		5		(47	)		27,261
Certificates of deposit		11,838		6		—		(63	)		11,781

Total investments	$	59,297	$	179	$	5	$	(133	)	$	59,348

Available For Sale Securities Debt Maturities Fair Value [Table Text Block]

	2015		2014
Maturing in one year or less	$	23,700	$	18,232
Maturing after one year through two years		27,183		25,459
Maturing after two years		20,604		15,657

Total investments	$	71,487	$	59,348

Schedule of Receivables from Collaborations [Table Text Block]

	September 30, 2015
	Billed		Unbilled		Total
U.S. Department of Health and Human Services	$	—	$	5,444	$	5,444
Green Cross Corporation		129		—		129
Seqirus UK Limited		1,922		—		1,922
Total receivables	$	2,051	$	5,444	$	7,495

	December 31, 2014
	Billed		Unbilled		Total
U.S. Department of Health and Human Services	$	—	$	2,778	$	2,778
Shionogi & Co. Ltd.		1,071		—		1,071
Total receivables	$	1,071	$	2,778	$	3,849

Schedule of Inventory, Current [Table Text Block]

	2015		2014
Work in process	$	—	$	267
Finished Goods		—		416

Net inventories	$	—	$	683

Schedule of Revenues from Collaborations [Table Text Block]

	Three Months				Nine Months
	2015		2014		2015		2014
Product sales, net	$	5,699	$	—	$	6,236	$	—
Royalty revenue		126		5		1,776		1,951
Collaborative and other research and development revenues:
U.S. Department of Health and Human Services		4,582		2,937		12,788		5,323
Green Cross Corporation		132		—		132		—
Shionogi (Japan)		296		296		888		888
Seqirus UK Limited		152		—		21,835		—
Total collaborative and other research and development revenues		5,162		3,233		35,643		6,211

Total revenues	$	10,987	$	3,238	$	43,655	$	8,162

- Definition

Tabular disclosure of available-for-sale securities which includes, but is not limited to, changes in the cost basis and fair value, fair value and gross unrealized gain (loss), fair values by type of security, contractual maturity and classification, amortized cost basis, contracts to acquire securities to be accounted for as available-for-sale, debt maturities, transfers to trading, change in net unrealized holding gain (loss) net of tax, continuous unrealized loss position fair value, aggregate losses qualitative disclosures, other than temporary impairment (OTTI) losses or other disclosures related to available for sale securities.

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