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Note 1 - Summary of Revenues (Details) - USD ($) $ in Thousands	3 Months Ended		9 Months Ended
	Sep. 30, 2015	Sep. 30, 2014	Sep. 30, 2015	Sep. 30, 2014
US Department of Health and Human Services [Member]
Collaborative and other research and development revenues:
U.S. Department of Health and Human Services	$ 4,582	$ 2,937	$ 12,788	$ 5,323
Green Cross Corporation [Member]
Collaborative and other research and development revenues:
U.S. Department of Health and Human Services	132		132
Shionogi and Co. Ltd [Member]
Collaborative and other research and development revenues:
U.S. Department of Health and Human Services	296	$ 296	888	$ 888
CSL [Member]
Collaborative and other research and development revenues:
U.S. Department of Health and Human Services	152		21,835
Product sales, net	5,699		6,236
Royalty revenue	126	$ 5	1,776	$ 1,951
U.S. Department of Health and Human Services	5,162	3,233	35,643	6,211
Revenues	$ 10,987	$ 3,238	$ 43,655	$ 8,162

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+ References

Reference 1: http://www.xbrl.org/2003/role/presentationRef



-Publisher FASB



-Name Accounting Standards Codification



-Topic 225



-SubTopic 10



-Section S99



-Paragraph 2



-Subparagraph (SX 210.5-03.1)



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+ References

Reference 1: http://www.xbrl.org/2003/role/presentationRef



-Publisher FASB



-Name Accounting Standards Codification



-Topic 225



-SubTopic 10



-Section S99



-Paragraph 2



-Subparagraph (SX 210.5-03.1(e))



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+ References

Reference 1: http://www.xbrl.org/2003/role/presentationRef



-Publisher FASB



-Name Accounting Standards Codification



-Topic 225



-SubTopic 10



-Section S99



-Paragraph 2



-Subparagraph (SX 210.5-03.1(a))



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