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Note 4 - Lease Obligations and Other Contingencies (Details Textual) | 12 Months Ended
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Dec. 31, 2015 USD ($) ft² | Dec. 31, 2014 USD ($) | Dec. 31, 2013 USD ($)
Birmingham Research Facility [Member] | Leasehold Improvements [Member] |  |  |
Property, Plant and Equipment, Gross | $ 1,589,000 |  |
Birmingham Research Facility [Member] | Long Term Liabilities [Member] |  |  |
Lease Financing Obligation, Net of Current | 2,375,000 |  |
Birmingham Research Facility [Member] |  |  |
Operating Leases, Future Minimum Payments Due | 4,839,000 |  |
Leasehold Improvements [Member] |  |  |
Property, Plant and Equipment, Gross | $ 5,610,000 | $ 5,303,000 |
Area of Real Estate Property | ft² | 32,000 |  |
Operating Leases, Future Minimum Payments Due |  | 6,908,000 |
Operating Leases, Rent Expense, Net | $ 664,000 | 633,000 | $ 526,000
Property, Plant and Equipment, Gross | 19,354,000 | $ 14,232,000 |
Lease Financing Obligation, Net of Current | $ 2,375 |  |

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- Definition Amount of required minimum rental payments for leases having an initial or remaining non-cancelable letter-terms in excess of one year. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 840 -SubTopic 10 -Section 55 -Paragraph 40 -Subparagraph (Note 3) -URI http://asc.fasb.org/extlink&oid=6584154&loc=d3e38371-112697 Reference 2: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 840 -SubTopic 20 -Section 50 -Paragraph 2 -Subparagraph (a) -URI http://asc.fasb.org/extlink&oid=6453985&loc=d3e41502-112717 + Details
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- Definition Rental expense for the reporting period incurred under operating leases, including minimum and any contingent rent expense, net of related sublease income. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 840 -SubTopic 20 -Section 50 -Paragraph 1 -URI http://asc.fasb.org/extlink&oid=6453985&loc=d3e41499-112717 + Details
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- Definition Amount before accumulated depreciation, depletion and amortization of physical assets used in the normal conduct of business and not intended for resale. Examples include, but are not limited to, land, buildings, machinery and equipment, office equipment, and furniture and fixtures. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 360 -SubTopic 10 -Section 50 -Paragraph 1 -Subparagraph (b) -URI http://asc.fasb.org/extlink&oid=6391035&loc=d3e2868-110229 Reference 2: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 210 -SubTopic 10 -Section S99 -Paragraph 1 -Subparagraph (SX 210.5-02.13) -URI http://asc.fasb.org/extlink&oid=6877327&loc=d3e13212-122682 + Details
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