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Note 9 - Collaborative and Other Research and Development Contracts (Details Textual) - USD ($) $ in Thousands		1 Months Ended							9 Months Ended	12 Months Ended	50 Months Ended
	Jun. 16, 2015	Sep. 30, 2013	Feb. 24, 2011	May. 31, 2010	Sep. 30, 2009	Jan. 31, 2007	Jun. 30, 2006	Feb. 28, 2006	Sep. 30, 2015	Dec. 31, 2015	Feb. 24, 2011	Mar. 31, 2015	Nov. 11, 2011	Dec. 31, 2007
US Department of Health and Human Services [Member]
Collaborative Agreement Contract Value						$ 102,661
Collaborative Agreement Additional Contract Value			$ 55,000		$ 77,191
Collaborative Agreement Adjusted Contract Value											$ 234,852
National Institute of Allergy and Infectious Diseases [Member]
Proceeds from awards for Research and Development Contracts		$ 5,000
Expected Receivable From Awards for Research and Development Contracts										$ 34,002
Collaborative Agreement Period of Contract										5 years
Collaboration Agreement Additional Payments Received										$ 29,875
UAB [Member]
Period of Agreement										25 years
Renewable Period of Agreement										5 years
Base Contract [Member]
Government Contract Receivable												$ 13,314
Additional Development Options [Member]
Government Contract Receivable												22,855
ASPRBARDA Contract [Member]
Government Contract Receivable												$ 36,169
Proceeds from awards for Research and Development Contracts									$ 16,300
Green Cross Corporation [Member]
Proceeds from License Fees Received							$ 250
Mundipharma [Member] | Upfront Payment [Member]
Deferred Revenue								$ 10,000
Mundipharma [Member] | Clinical Trial 2007 [Member]
Deferred Revenue														$ 5,000
Mundipharma [Member]
Upfront Payments Receivable Amount								$ 10,000
Potential Milestone Payments Receivable													$ 15,000
AECOM and IRL [Member]
Milestone Payment Maximum										$ 4,000
Milestone Payment Minimum										1,400
Annual License Fee Minimum										150
Annual License Fee Maximum										$ 500
Advance Notice Period for Termination of Agreement										60 days
Stock Issued During Period, Value, for Modification of License Agreement				$ 5,911
Payments for Modification of License Agreement				$ 90
CSL Limited [Member
Proceeds from License Fees Received	$ 33,740
Milestone Payment Maximum	$ 12,000
Royalty Term	10 years

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- Definition

Represents advance notice period for termination of agreement.

+ References

No definition available.

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- Definition

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- Definition

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- Definition

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+ References

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- Definition

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- Definition

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- Definition

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- Definition

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- Definition

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- Definition

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- Definition

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No definition available.

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- Definition

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No definition available.

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- Definition

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+ References

No definition available.

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- Definition

Represents renewable period of agreement.

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- Definition

Period of time between the date of the Agreement and its expiration.

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- Definition

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- Definition

Amount of deferred revenue as of balance sheet date. Deferred revenue represents collections of cash or other assets related to a revenue producing activity for which revenue has not yet been recognized. Generally, an entity records deferred revenue when it receives consideration from a customer before achieving certain criteria that must be met for revenue to be recognized in conformity with GAAP.

+ References

Reference 1: http://www.xbrl.org/2003/role/presentationRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 605
-SubTopic 10
-Section S99
-Paragraph 1
-Subparagraph (SAB TOPIC 13.A.4(a).Q1 Response)
-URI http://asc.fasb.org/extlink&oid=27012821&loc=d3e214044-122780

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- Definition

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+ References

Reference 1: http://www.xbrl.org/2003/role/presentationRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 912
-SubTopic 310
-Section 45
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Cash received from licensees for license fees during the current period.

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Reference 1: http://www.xbrl.org/2003/role/presentationRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 230
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-Section 45
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