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Note 1 - Summary of Revenues (Details) - USD ($) $ in Thousands	3 Months Ended
	Mar. 31, 2016	Mar. 31, 2015
US Department of Health and Human Services [Member]
Collaborative and other research and development revenues:
Collaborative and other research and development revenues	$ 2,324	$ 4,475
Shionogi and Co. Ltd [Member]
Collaborative and other research and development revenues:
Collaborative and other research and development revenues	296	$ 296
Seqirus UK Limited [Member]
Collaborative and other research and development revenues:
Collaborative and other research and development revenues	$ 310
Product sales, net		$ 537
Royalty revenue	$ 1,890	1,518
Collaborative and other research and development revenues	2,930	4,771
Revenues	$ 4,820	$ 6,826

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+ References

No definition available.

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+ References

Reference 1: http://www.xbrl.org/2003/role/presentationRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 225
-SubTopic 10
-Section S99
-Paragraph 2
-Subparagraph (SX 210.5-03.1)
-URI http://asc.fasb.org/extlink&oid=63488584&loc=d3e20235-122688

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+ References

Reference 1: http://www.xbrl.org/2003/role/presentationRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 225
-SubTopic 10
-Section S99
-Paragraph 2
-Subparagraph (SX 210.5-03.1(e))
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+ References

Reference 1: http://www.xbrl.org/2003/role/presentationRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 225
-SubTopic 10
-Section S99
-Paragraph 2
-Subparagraph (SX 210.5-03.1(a))
-URI http://asc.fasb.org/extlink&oid=63488584&loc=d3e20235-122688

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