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Note 4 - Royalty Monetization (Details Textual)		3 Months Ended
	Mar. 09, 2011 USD ($)	Mar. 31, 2016 USD ($)	Mar. 31, 2015 USD ($)	Mar. 31, 2016 JPY (¥)	Dec. 31, 2015 USD ($)	Sep. 30, 2015	Dec. 31, 2013 USD ($)
PhaRMA Notes Member] | JPR Royalty Sub LLC [Member] | Currency Hedge Agreement [Member]
Collateral Already Posted, Aggregate Fair Value		$ 0	$ 0
Maximum Amount of Collateral Required to Post					$ 9,750,000
PhaRMA Notes Member] | JPR Royalty Sub LLC [Member] | Fair Value, Inputs, Level 2 [Member]
Notes Payable, Fair Value Disclosure							$ 30,000,000
PhaRMA Notes Member] | JPR Royalty Sub LLC [Member]
Private Placement of Senior Secured Notes	$ 30,000,000
Debt Instrument, Interest Rate, Stated Percentage	14.00%
PhaRMA Notes Member] | Currency Hedge Agreement [Member] | Japan, Yen [Member]
Derivative, Forward Exchange Rate						100
PhaRMA Notes Member] | Currency Hedge Agreement [Member]
Payments for (Proceeds from) Hedge, Investing Activities		$ 1,950,000
Required Foreign Currency Hedge Per Dollar | ¥				¥ 100
PhaRMA Notes Member] | JPR Royalty Sub LLC [Member]
Percentage of Carrying Amount in Excess of Fair Value		50.00%		50.00%
JPR Royalty Sub LLC [Member] | Royalty Monetization [Member]
Revenue Recognition Royalty and Milestone Revenue Recognized	$ 30,000,000
Revenue Recognition Royalty And Milestone Revenue Recognized, Net	22,691,000
Transaction Costs	4,309,000
Interest Reserve	3,000,000
Currency Hedge Agreement [Member]
Collateral Already Posted, Aggregate Fair Value		$ 0			$ 0
Foreign Exchange Contract [Member] | Not Designated as Hedging Instrument [Member]
Derivative, Loss on Derivative		$ 2,753,000
Derivative, Gain on Derivative			$ 464,000
JPR Royalty Sub LLC [Member]
Revenue Recognition Royalty and Milestone Revenue Recognized	$ 30,000,000

X

- Definition

Represents interest reserve established as part of the royalty monetization.

+ References

No definition available.

+ Details

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X

- Definition

Represents maximum amount of collateral required to post.

+ References

No definition available.

+ Details

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- Definition

Represents the percentage of carrying amount in excess of fair value.

+ References

No definition available.

+ Details

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X

- Definition

Represents private placement of senior secured notes.

+ References

No definition available.

+ Details

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- Definition

The Company is required to maintain a foreign currency hedge per dollar under the agreements governing the PhaRMA Notes.

+ References

No definition available.

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- Definition

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+ References

No definition available.

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- Definition

Revenue recognition royalty and milestone revenue recognized.

+ References

No definition available.

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- Definition

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+ References

No definition available.

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- Definition

The aggregate fair value of assets that are already posted, at the end of the reporting period, as collateral for derivative instruments with credit-risk-related contingent features.

+ References

Reference 1: http://www.xbrl.org/2003/role/presentationRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 815
-SubTopic 10
-Section 50
-Paragraph 4H
-Subparagraph (d)
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- Definition

Contractual interest rate for funds borrowed, under the debt agreement.

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-Publisher FASB
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-Section S99
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Contractual rate at which a foreign currency can be purchased or sold.

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- Definition

Amount of increase in the fair value of derivatives recognized in the income statement.

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Amount of decrease in the fair value of derivatives recognized in the income statement.

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- Definition

Fair value portion of notes payable.

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- Definition

The cash outflow or inflow for a financial contract that meets the hedge criteria as either a cash flow hedge, fair value hedge, or hedge of a net investment in a foreign operation.

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