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Note 1 - Significant Accounting Policies (Tables)

6 Months Ended

Jun. 30, 2016

Notes Tables

Available-for-sale Securities [Table Text Block]

		June 30, 2016
		Amortized Cost				Accrued Interest				Gross Unrealized Gains				Gross Unrealized Losses				Estimated Fair Value
Obligations of the U.S. Government and its agencies		$	14,081			$	38			$	8			$	—			$	14,127
Corporate debt securities			16,641				147				23				(1	)			16,810
Certificates of deposit			20,258				22				23				(7	)			20,296
Total investments		$	50,980			$	207			$	54			$	(8	)		$	51,233

		December 31, 2015
		Amortized Cost				Accrued Interest				Gross Unrealized Gains				Gross Unrealized Losses				Estimated Fair Value
Obligations of the U.S. Government and its agencies		$	26,557			$	88			$	—			$	(99	)		$	26,546
Corporate debt securities			21,820				184				—				(41	)			21,963
Certificates of deposit			21,884				21				5				(72	)			21,838
Total investments		$	70,261			$	293			$	5			$	(212	)		$	70,347

Available For Sale Securities Debt Maturities Fair Value [Table Text Block]

		2016				2015
Maturing in one year or less		$	27,079			$	22,664
Maturing after one year through two years			18,164				28,395
Maturing after two years			5,990				19,288
Total investments		$	51,233			$	70,347

Schedule of Receivables from Collaborations [Table Text Block]

		June 30, 2016
		Billed				Unbilled				Total
U.S. Department of Health and Human Services		$	723			$	1,273			$	1,996
Shionogi & Co. Ltd.			145				—				145
Seqirus UK Limited			37				56				93
Total receivables		$	905			$	1,329			$	2,234

		December 31, 2015
		Billed				Unbilled				Total
U.S. Department of Health and Human Services		$	—			$	5,536			$	5,536
Shionogi & Co. Ltd.			469				—				469
Seqirus UK Limited			210				28				238
Total receivables		$	679			$	5,564			$	6,243

Schedule of Inventory, Current [Table Text Block]

		2016				2015
Work in process		$	1,949			$	1,612
Inventories		$	1,949			$	1,612

Schedule of Revenues from Collaborations [Table Text Block]

		Three Months								Six Months
		2016				2015				2016				2015
Product sales, net		$	—			$	—			$	—			$	537
Royalty revenue			629				132				2,519				1,650
Collaborative and other research and development revenues:
U.S. Department of Health and Human Services			3,709				3,731				6,033				8,206
Shionogi (Japan)			296				296				592				592
Seqirus UK Limited			153				21,683				463				21,683
Total collaborative and other research and development revenues			4,158				25,710				7,088				30,481
Total revenues		$	4,787			$	25,842			$	9,607			$	32,668

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