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Note 1 - Significant Accounting Policies (Tables)

9 Months Ended

Sep. 30, 2016

Notes Tables

Available-for-sale Securities [Table Text Block]

		September 30, 2016
		Amortized Cost				Accrued Interest				Gross Unrealized Gains				Gross Unrealized Losses				Estimated Fair Value
Obligations of the U.S. Government and its agencies		$	6,186			$	15			$	3			$	—			$	6,204
Corporate debt securities			7,187				24				5				(1	)			7,215
Certificates of deposit			18,342				29				19				(4	)			18,386
Total investments		$	31,715			$	68			$	27			$	(5	)		$	31,805

		December 31, 2015
		Amortized Cost				Accrued Interest				Gross Unrealized Gains				Gross Unrealized Losses				Estimated Fair Value
Obligations of the U.S. Government and its agencies		$	26,557			$	88			$	—			$	(99	)		$	26,546
Corporate debt securities			21,820				184				—				(41	)			21,963
Certificates of deposit			21,884				21				5				(72	)			21,838
Total investments		$	70,261			$	293			$	5			$	(212	)		$	70,347

Available For Sale Securities Debt Maturities Fair Value [Table Text Block]

		2016				2015
Maturing in one year or less		$	17,434			$	22,664
Maturing after one year through two years			14,371				28,395
Maturing after two years			—				19,288
Total investments		$	31,805			$	70,347

Schedule of Receivables from Collaborations [Table Text Block]

		September 30, 2016
		Billed				Unbilled				Total
U.S. Department of Health and Human Services		$	83			$	1,746			$	1,829
Shionogi & Co. Ltd.			3,902				—				3,902
Green Cross Corporation			9				—				9
Seqirus UK Limited			—				228				228
Total receivables		$	3,994			$	1,974			$	5,968

		December 31, 2015
		Billed				Unbilled				Total
U.S. Department of Health and Human Services		$	—			$	5,536			$	5,536
Shionogi & Co. Ltd.			469				—				469
Seqirus UK Limited			210				28				238
Total receivables		$	679			$	5,564			$	6,243

Schedule of Inventory, Current [Table Text Block]

		2016				2015
Work in process		$	2,232			$	1,612
Inventories		$	2,232			$	1,612

Schedule of Revenues from Collaborations [Table Text Block]

		Three Months								Nine Months
		2016				2015				2016				2015
Product sales, net		$	—			$	5,699			$	—			$	6,236
Royalty revenue			3,501				126				6,020				1,776
Collaborative and other research and development revenues:
U.S. Department of Health and Human Services			3,813				4,582				9,846				12,788
Green Cross Corporation			—				132				—				132
Shionogi (Japan)			296				296				888				888
Seqirus UK Limited			153				152				616				21,835
Total collaborative and other research and development revenues			4,262				5,162				11,350				35,643
Total revenues		$	7,763			$	10,987			$	17,370			$	43,655

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