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Note 10 - Collaborative and Other Research and Development Contracts (Details Textual) - USD ($)		1 Months Ended								12 Months Ended		40 Months Ended	50 Months Ended
	Jun. 16, 2015	Sep. 30, 2013	Feb. 24, 2011	May 31, 2010	Sep. 30, 2009	Jan. 31, 2007	Jun. 30, 2006	Feb. 28, 2006	Jun. 30, 2000	Dec. 31, 2016	Dec. 31, 2015	Dec. 31, 2016	Feb. 24, 2011	Mar. 31, 2015	Nov. 11, 2011
CSL Limited [Member
Proceeds from License Fees Received	$ 33,740,000
Milestone Payment Maximum	$ 12,000,000
Base Contract [Member]
Government Contract Receivable														$ 16,265,000
Additional Development Options [Member]
Government Contract Receivable														22,855,000
ASPRBARDA Contract [Member]
Government Contract Receivable														$ 39,120,000
Proceeds from awards for Research and Development Contracts										$ 20,574,000
Green Cross Corporation [Member]
Proceeds from License Fees Received							$ 250,000
Mundipharma [Member]
Upfront Payments Receivable Amount								$ 10,000,000
Potential Milestone Payments Receivable															$ 15,000,000
Mundipharma [Member] | Upfront Payment [Member]
Deferred Revenue								$ 5,000,000
AECOM and IRL [Member]
Milestone Payment Maximum									$ 4,000,000
Milestone Payment Minimum									1,400,000
Annual License Fee Minimum									150,000
Annual License Fee Maximum									$ 500,000
Advance Notice Period for Termination of Agreement									60 days
Stock Issued During Period, Value, for Modification of License Agreement				$ 5,911,000
Payments for Modification of License Agreement				$ 90,000
US Department of Health and Human Services [Member]
Collaborative Agreement Contract Value						$ 102,661,000
Collaborative Agreement Additional Contract Value			$ 55,000,000		$ 77,191,000
Collaborative Agreement Adjusted Contract Value													$ 234,852,000
National Institute of Allergy and Infectious Diseases [Member]
Proceeds from awards for Research and Development Contracts		$ 5,000,000
Expected Receivable From Awards for Research and Development Contracts												$ 39,477
UAB [Member]
Period of Agreement											25 years

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- Definition

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- Definition

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- Definition

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Amount of deferred revenue as of balance sheet date. Deferred revenue represents collections of cash or other assets related to a revenue producing activity for which revenue has not yet been recognized. Generally, an entity records deferred revenue when it receives consideration from a customer before achieving certain criteria that must be met for revenue to be recognized in conformity with GAAP.

+ References

Reference 1: http://www.xbrl.org/2003/role/presentationRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 605
-SubTopic 10
-Section S99
-Paragraph 1
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