XML 16 R5.htm IDEA: XBRL DOCUMENT v3.7.0.1
Consolidated Statements of Cash Flows (Unaudited) - USD ($)
 3 Months Ended
Mar. 31, 2017
Mar. 31, 2016
Operating activities    
Net loss $ (14,219,000) $ (22,832,000)
Adjustments to reconcile net loss to net cash used in operating activities:    
Depreciation and amortization 172,000 47,000
Stock-based compensation expense 2,462,000 2,645,000
Amortization of Debt Issuance Costs 220,000 110,000
Amortization of premium/discount on investments 18,000 233,000
Change in fair value of foreign currency derivative 1,543,000 2,753,000
Changes in operating assets and liabilities:    
Receivables (796,000) (1,141,000)
Inventory (155,000) (337,000)
Prepaid expenses and other assets (284,000) (546,000)
Deferred collaboration expense 18,000 19,000
Accounts payable and accrued expenses 1,642,000 (541,000)
Interest payable 1,301,000 1,228,000
Deferred revenue (449,000) (480,000)
Net cash used in operating activities (8,527,000) (18,842,000)
Investing activities    
Acquisitions of property and equipment (3,000) (3,260,000)
Change in restricted cash (1,252,000) (353,000)
Sales and maturities of investments 14,136,000 6,320,000
Net cash provided by investing activities 12,881,000 2,707,000
Financing activities    
Sale of common stock, net 47,750,000
Net proceeds from common stock issued under stock-based compensation plans 950,000 7,000
Increase in lease financing obligation 131,000
Net cash provided by financing activities 48,700,000 138,000
Increase (decrease) in cash and cash equivalents 53,054,000 (15,997,000)
Cash and cash equivalents at beginning of period 22,104,000 28,899,000
Cash and cash equivalents at end of period $ 75,158,000 $ 12,902,000