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v3.7.0.1

Consolidated Statements of Cash Flows (Unaudited) - USD ($) $ in Thousands | 6 Months Ended
--- | ---
Jun. 30, 2017 | Jun. 30, 2016
Operating activities |  |
Net loss | $ (31,105) | $ (39,113)
Adjustments to reconcile net loss to net cash used in operating activities: |  |
Depreciation and amortization | 344 | 136
Stock-based compensation expense | 4,788 | 4,491
Amortization of Debt Issuance Costs | 439 | 220
Amortization of premium/discount on investments | 86 | 302
Change in fair value of foreign currency derivative | 1,943 | 6,441
Changes in operating assets and liabilities: |  |
Receivables | 5,443 | 4,009
Inventory | (805) | (337)
Prepaid expenses and other assets | (87) | 1,000
Deferred collaboration expense | 35 | 37
Accounts payable and accrued expenses | (975) | (8,742)
Interest payable | 2,597 | 2,457
Deferred revenue | (897) | (927)
Net cash used in operating activities | (18,194) | (30,026)
Investing activities |  |
Acquisitions of property and equipment | (24) | (5,099)
Change in restricted cash | (3,811) | (2,814)
Purchases of investments | (33,070) |
Sales and maturities of investments | 23,873 | 19,064
Net cash (used in) provided by investing activities | (13,032) | 11,151
Financing activities |  |
Sale of common stock, net | 47,750 |
Net proceeds from common stock issued under stock-based compensation plans | 1,068 | 33
Payment of foreign currency derivative collateral |  | (1,610)
Increase in lease financing obligation |  | 214
Net cash provided by (used in) financing activities | 48,818 | (1,363)
Increase (decrease) in cash and cash equivalents | 17,592 | (20,238)
Cash and cash equivalents at beginning of period | 22,104 | 28,899
Cash and cash equivalents at end of period | $ 39,696 | $ 8,661

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