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Note 2 - Property and Equipment | 12 Months Ended
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Dec. 31, 2017
Notes to Financial Statements |
Property, Plant and Equipment Disclosure [Text Block] | Note 2 — Property and Equipment Property and equipment consisted of the following at December 31:
|  | 2017 |  | 2016
Furniture and fixtures |  | $ | 566 |  |  | $ | 540 |
Office equipment |  |  | 146 |  |  |  | 141 |
Software |  |  | 1,125 |  |  |  | 1,117 |
Laboratory equipment |  |  | 2,984 |  |  |  | 3,252 |
Leased equipment |  |  | 152 |  |  |  | — |
Leasehold improvements |  |  | 8,405 |  |  |  | 8,294 |
Building |  |  | 1,495 |  |  |  | 1,495 |
|  |  | 14,873 |  |  |  | 14,839 |
Less accumulated depreciation and amortization |  |  | (5,327 | ) |  |  | (4,917 | )
Property and equipment, net |  | $ | 9,546 |  |  | $ | 9,922 |
Depreciation and amortization expense for the years ended December 31, 2017, 2016 and 2015 was $704, $483 and $180, respectively.

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- Definition The entire disclosure for long-lived, physical assets used in the normal conduct of business and not intended for resale. Includes, but is not limited to, accounting policies and methodology, roll forwards, depreciation, depletion and amortization expense, including composite depreciation, accumulated depreciation, depletion and amortization expense, useful lives and method used, income statement disclosures, assets held for sale and public utility disclosures. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 360 -URI http://asc.fasb.org/topic&trid=2155823 + Details
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