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Note 6 - Stockholders' Equity
 12 Months Ended
Dec. 31, 2017
Notes to Financial Statements  
Stockholders' Equity Note Disclosure [Text Block]
Note 
6
 — Stockholders’ Equity
 
Sales of Common Stock
 
In
March 2017,
the Company completed a public offering of
6,061
shares of its common stock at a price of
$8.50
per share, which included the underwriters’ overallotment option to purchase additional shares. Net proceeds were approximately
$47,750
after deducting underwriting discounts and offering expenses.
 
In
September 2017,
the Company completed a public offering of
17,864
shares of its common stock at a price of
$5.15
per share, which included the underwriters’ overallotment option to purchase additional shares. Net proceeds were approximately
$86,250
after deducting underwriting discounts and offering expenses.
 
On
November 8, 2017,
the Company filed a
$200,000
shelf registration statement on Form S-
3
with the SEC. This shelf registration statement became effective on
December 12, 2017
and allows the Company to sell securities, including common stock, preferred stock, depository shares, stock purchase contracts, warrants and units, from time to time at prices and on terms to be determined at the time of sale.