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Note 11 - Quarterly Financial Information (Unaudited)
 12 Months Ended
Dec. 31, 2017
Notes to Financial Statements  
Quarterly Financial Information [Text Block]
Note 
11
 — Quarterly Financial Information (Unaudited)
 
    First   Second   Third   Fourth
2017 Quarters                                
Revenues   $
9,437
     $
3,099
     $
8,760
     $
3,890
  
Net Loss    
(14,219
 )    
(16,886
 )    
(15,134
 )    
(19,543
 )
Basic and diluted net loss per share    
(0.19
 )    
(0.21
 )    
(0.18
 )    
(0.20
 )
2016 Quarters                                
Revenues   $
4,820
     $
4,787
     $
7,763
     $
8,983
  
Net Loss    
(22,832
 )    
(16,281
 )    
(11,528
 )    
(4,503
 )
Basic and diluted net loss per share    
(0.31
 )    
(0.22
 )    
(0.16
 )    
(0.06
 )