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Note 3 - Royalty Monetization (Details Textual) $ in Thousands			12 Months Ended
	May 18, 2016 USD ($)	Mar. 09, 2011 USD ($)	Dec. 31, 2017 USD ($)	Dec. 31, 2016 USD ($)	Dec. 31, 2015 USD ($)	May 18, 2016 JPY (¥)	Sep. 30, 2013
Currency Hedge Agreement [Member]
Collateral Already Posted, Aggregate Fair Value			$ 0	$ 0
Foreign Exchange Contract [Member] | Not Designated as Hedging Instrument [Member]
Derivative, Loss on Derivative			1,787	1,654	$ 564
Derivative, Gain on Derivative			$ 966	811	$ 1,654
PhaRMA Notes Member] | Currency Hedge Agreement [Member]
Payments for (Proceeds from) Hedge, Investing Activities	$ 1,950
Required Foreign Currency Hedge Per Dollar | ¥						¥ 100
PhaRMA Notes Member] | Japan, Yen | Currency Hedge Agreement [Member]
Derivative, Forward Exchange Rate			100
JPR Royalty Sub LLC [Member] | PhaRMA Notes Member]
Private Placement of Senior Secured Notes		$ 30,000
Debt Instrument, Interest Rate, Stated Percentage		14.00%					14.00%
Percentage of Carrying Amount in Excess of Fair Value			50.00%
JPR Royalty Sub LLC [Member] | PhaRMA Notes Member] | Currency Hedge Agreement [Member]
Collateral Already Posted, Aggregate Fair Value			$ 0	$ 0
Maximum Amount of Collateral Required to Post			5,850
JPR Royalty Sub LLC [Member] | PhaRMA Notes Member] | Fair Value, Inputs, Level 2 [Member]
Notes Payable, Fair Value Disclosure			$ 30,000
JPR Royalty Sub LLC [Member] | Royalty Monetization [Member]
Debt Instrument, Face Amount		$ 30,000
Proceeds from Issuance of Secured Debt		22,691
Transaction Costs		4,309
Interest Reserve		$ 3,000

X

- Definition

Represents interest reserve established as part of the royalty monetization.

+ References

No definition available.

+ Details

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- Definition

Represents maximum amount of collateral required to post.

+ References

No definition available.

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- Definition

Represents the percentage of carrying amount in excess of fair value.

+ References

No definition available.

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- Definition

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+ References

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- Definition

The Company is required to maintain a foreign currency hedge per dollar under the agreements governing the PhaRMA Notes.

+ References

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- Definition

Represents transaction costs associated with royalty monetization.

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- Definition

The aggregate fair value of assets that are already posted, at the end of the reporting period, as collateral for derivative instruments with credit-risk-related contingent features.

+ References

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-Publisher FASB
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-SubTopic 10
-Section 50
-Paragraph 4H
-Subparagraph (d)
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- Definition

Face (par) amount of debt instrument at time of issuance.

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- Definition

Contractual interest rate for funds borrowed, under the debt agreement.

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- Definition

Contractual rate at which a foreign currency can be purchased or sold.

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- Definition

Amount of increase in the fair value of derivatives recognized in the income statement.

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Amount of decrease in the fair value of derivatives recognized in the income statement.

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Fair value portion of notes payable.

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- Definition

The cash outflow or inflow for a financial contract that meets the hedge criteria as either a cash flow hedge, fair value hedge, or hedge of a net investment in a foreign operation.

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- Definition

The cash inflow from amounts received from issuance of long-term debt that is wholly or partially secured by collateral. Excludes proceeds from tax exempt secured debt.

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