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Note 2 - Property and Equipment
12 Months Ended
Dec. 31, 2017
Notes to Financial Statements  
Property, Plant and Equipment Disclosure [Text Block]
Note 
2
 — Property and Equipment
 
Property and equipment consisted of the following at
December 
31:
 
    2017   2016
Furniture and fixtures   $
566
    $
540
 
Office equipment    
146
     
141
 
Software    
1,125
     
1,117
 
Laboratory equipment    
2,984
     
3,252
 
Leased equipment    
152
     
 
Leasehold improvements    
8,405
     
8,294
 
Building    
1,495
     
1,495
 
     
14,873
     
14,839
 
Less accumulated depreciation and amortization    
(5,327
)    
(4,917
)
Property and equipment, net   $
9,546
    $
9,922
 
  
Depreciation and amortization expense for the years ended
December 
31,
2017,
2016
and
2015
was
$704,
$483
and
$180,
respectively.