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Note 4 - Royalty Monetization (Details Textual) $ in Thousands |  |  | 3 Months Ended |  |
--- | --- | --- | --- | --- | ---
May 18, 2016 USD ($) | Mar. 09, 2011 USD ($) | Mar. 31, 2018 USD ($) | Mar. 31, 2017 USD ($) | Dec. 31, 2017 USD ($) | May 18, 2016 JPY (¥)
Currency Hedge Agreement [Member] |  |  |  |  |  |
Collateral Already Posted, Aggregate Fair Value |  |  | $ 0 |  | $ 0 |
Foreign Exchange Contract [Member] | Not Designated as Hedging Instrument [Member] |  |  |  |  |  |
Derivative, Loss on Derivative |  |  | $ 1,804 | $ 1,543 |  |
PhaRMA Notes Member] | Currency Hedge Agreement [Member] |  |  |  |  |  |
Payments for (Proceeds from) Hedge, Investing Activities, Total | $ 1,950 |  |  |  |  |
Required Foreign Currency Hedge Per Dollar | ¥ |  |  |  |  |  | ¥ 100
PhaRMA Notes Member] | Japan, Yen | Currency Hedge Agreement [Member] |  |  |  |  |  |
Derivative, Forward Exchange Rate |  |  | 100 |  |  |
JPR Royalty Sub LLC [Member] | PhaRMA Notes Member] |  |  |  |  |  |
Private Placement of Senior Secured Notes |  | $ 30,000 |  |  |  |
Debt Instrument, Interest Rate, Stated Percentage |  | 14.00% |  |  |  |
Percentage of Carrying Amount in Excess of Fair Value |  |  | 50.00% |  |  |
JPR Royalty Sub LLC [Member] | PhaRMA Notes Member] | Currency Hedge Agreement [Member] |  |  |  |  |  |
Collateral Already Posted, Aggregate Fair Value |  |  | $ 0 |  | $ 0 |
Maximum Amount of Collateral Required to Post |  |  | 5,850 |  |  |
JPR Royalty Sub LLC [Member] | PhaRMA Notes Member] | Fair Value, Inputs, Level 2 [Member] |  |  |  |  |  |
Notes Payable, Fair Value Disclosure |  |  | $ 30,000 |  |  |
JPR Royalty Sub LLC [Member] | Royalty Monetization [Member] |  |  |  |  |  |
Debt Instrument, Face Amount |  | $ 30,000 |  |  |  |
Proceeds from Issuance of Secured Debt |  | 22,691 |  |  |  |
Transaction Costs |  | 4,309 |  |  |  |
Interest Reserve |  | $ 3,000 |  |  |  |

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