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v3.10.0.1

Consolidated Statements of Cash Flows (Unaudited) - USD ($) $ in Thousands | 6 Months Ended
--- | ---
Jun. 30, 2018 | Jun. 30, 2017
Operating activities |  |
Net loss | $ (44,223) | $ (31,105)
Adjustments to reconcile net loss to net cash used in operating activities: |  |
Depreciation and amortization | 377 | 344
Stock-based compensation expense | 4,987 | 4,788
Amortization of debt issuance costs | 455 | 439
Amortization of premium/discount on investments | 140 | 86
Change in fair value of foreign currency derivative | 1,185 | 1,943
Changes in operating assets and liabilities: |  |
Receivables | 3,775 | 5,443
Inventory | (221) | (805)
Prepaid expenses and other assets | (347) | (87)
Deferred collaboration expense | 140 | 35
Accounts payable and accrued expenses | 4,447 | (975)
Interest payable | 2,737 | 2,597
Deferred revenue | (7,000) | (897)
Net cash used in operating activities | (33,548) | (18,194)
Investing activities |  |
Acquisitions of property and equipment | (221) | (24)
Purchases of investments | (16,754) | (33,070)
Sales and maturities of investments | 34,435 | 23,873
Net cash provided by (used in) investing activities | 17,460 | (9,221)
Financing activities |  |
Sale of common stock, net |  | 47,750
Payment of senior credit facility | (3,450) |
Net proceeds from common stock issued under stock-based compensation plans | 736 | 1,068
Increase in lease financing obligation | (37) |
Net cash (used in) provided by financing activities | (2,751) | 48,818
(Decrease) increase in cash, cash equivalents and restricted cash | (18,839) | 21,403
Cash, cash equivalents and restricted cash at beginning of period | 53,568 | 23,650
Cash, cash equivalents and restricted cash at end of period | $ 34,729 | $ 45,053

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