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Note 10 - Collaborative and Other Research and Development Contracts (Details Textual) - USD ($) $ in Thousands |  |  | 1 Months Ended | 9 Months Ended | 12 Months Ended | 42 Months Ended | 43 Months Ended |  |
--- | --- | --- | --- | --- | --- | --- | --- | --- | ---
Jun. 16, 2015 | Feb. 28, 2006 | Jan. 31, 2007 | Jun. 30, 2006 | Jun. 30, 2000 | Sep. 30, 2018 | Dec. 31, 2018 | Sep. 30, 2018 | Dec. 31, 2018 | Mar. 31, 2015 | Nov. 11, 2011
CSL Limited [Member |  |  |  |  |  |  |  |  |  |  |
Milestone Payment Received |  |  |  |  |  |  |  |  | $ 12,000 |  |
Royalty Term | 10 years |  |  |  |  |  |  |  |  |  |
Base Contract [Member] |  |  |  |  |  |  |  |  |  |  |
Government Contract Receivable |  |  |  |  |  |  |  |  |  | $ 16,265 |
Additional Development Options [Member] |  |  |  |  |  |  |  |  |  |  |
Government Contract Receivable |  |  |  |  |  |  |  |  |  | 22,855 |
ASPRBARDA Contract [Member] |  |  |  |  |  |  |  |  |  |  |
Government Contract Receivable |  |  |  |  |  |  |  |  |  | $ 39,120 |
Proceeds from awards for Research and Development Contracts |  |  |  |  |  |  |  | $ 20,574 |  |  |
Green Cross Corporation [Member] |  |  |  |  |  |  |  |  |  |  |
Proceeds from License Fees Received |  |  |  | $ 250 |  |  |  |  |  |  |
Mundipharma [Member] |  |  |  |  |  |  |  |  |  |  |
Upfront Payments Receivable Amount |  | $ 10,000 |  |  |  |  |  |  |  |  |
Potential Milestone Payments Receivable |  |  |  |  |  |  |  |  |  |  | $ 15,000
AECOM and IRL [Member] |  |  |  |  |  |  |  |  |  |  |
Milestone Payment Minimum |  |  |  |  | $ 1,400 |  |  |  |  |  |
Milestone Payment Maximum |  |  |  |  | 4,000 |  |  |  |  |  |
Annual License Fee Minimum |  |  |  |  | 150 |  |  |  |  |  |
Annual License Fee Maximum |  |  |  |  | $ 500 |  |  |  |  |  |
Advance Notice Period for Termination of Agreement |  |  |  |  | 60 days |  |  |  |  |  |
National Institute of Allergy and Infectious Diseases [Member] |  |  |  |  |  |  |  |  |  |  |
Collaborative Agreement Contract Value |  |  | $ 5,000 |  |  |  |  |  |  |  |
Expected Receivable From Awards for Research and Development Contracts |  |  |  |  |  |  | $ 43,035 |  |  |  |
UAB [Member] |  |  |  |  |  |  |  |  |  |  |
Period of Agreement |  |  |  |  |  | 25 years |  |  |  |  |
Renewable Period of Agreement |  |  |  |  |  | 5 years |  |  |  |  |

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- Definition The amount of receivables that are derived from government contracts. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 912 -SubTopic 310 -Section 45 -Paragraph 1 -URI http://asc.fasb.org/extlink&oid=68054760&loc=d3e55295-109406 + Details
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