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Note 11 - Quarterly Financial Information (Unaudited) (Tables)
 12 Months Ended
Dec. 31, 2018
Notes Tables  
Quarterly Financial Information [Table Text Block]
    First   Second   Third   Fourth
2018 Quarters                                
Revenues   $
3,976
     $
12,494
     $
1,454
     $
2,729
  
Net Loss    
(25,777
 )    
(18,446
 )    
(29,597
 )    
(27,432
 )
Basic and diluted net loss per share    
(0.26
 )    
(0.19
 )    
(0.28
 )    
(0.25
 )
2017 Quarters                                
Revenues   $
9,437
     $
3,099
     $
8,760
     $
3,890
  
Net Loss    
(14,219
 )    
(16,886
 )    
(15,134
 )    
(19,543
 )
Basic and diluted net loss per share    
(0.19
 )    
(0.21
 )    
(0.18
 )    
(0.20
 )