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Note 2 - Property and Equipment
12 Months Ended
Dec. 31, 2018
Notes to Financial Statements  
Property, Plant and Equipment Disclosure [Text Block]
Note 
2
 — Property and Equipment
 
Property and equipment consisted of the following at
December 
31:
 
    2018   2017
Furniture and fixtures   $
573
    $
566
 
Office equipment    
152
     
146
 
Software    
1,125
     
1,125
 
Laboratory equipment    
3,329
     
2,984
 
Leased equipment    
143
     
152
 
Leasehold improvements    
8,413
     
8,405
 
Building    
1,495
     
1,495
 
     
15,230
     
14,873
 
Less accumulated depreciation and amortization    
(6,095
)    
(5,327
)
Property and equipment, net   $
9,135
    $
9,546
 
  
Depreciation and amortization expense for the years ended
December 
31,
2018,
2017
and
2016
was
$770,
$704
and
$483,
respectively.