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v3.19.2

Consolidated Statements of Comprehensive Loss (Unaudited) - USD ($) shares in Thousands, $ in Thousands | 3 Months Ended | 6 Months Ended
--- | --- | ---
Jun. 30, 2019 | Jun. 30, 2018 | Jun. 30, 2019 | Jun. 30, 2018
Revenues: |  |  |  |
Revenues | $ 1,448 | $ 12,494 | $ 7,335 | $ 16,470
Expenses |  |  |  |
Cost of product sales |  |  | 1,399 |
Research and development | 27,681 | 21,010 | 55,174 | 39,451
General and administrative | 8,659 | 9,492 | 14,897 | 17,101
Royalty | 26 | 243 | 113 | 383
Total operating expenses | 36,366 | 30,745 | 71,583 | 56,935
Loss from operations | (34,918) | (18,251) | (64,248) | (40,465)
Interest and other income | 547 | 493 | 1,143 | 955
Interest expense | (3,035) | (2,195) | (5,761) | (4,416)
(Loss) gain on foreign currency derivative | (223) | 1,507 | 183 | (297)
Net loss | (37,629) | (18,446) | (68,683) | (44,223)
Unrealized gain (loss) on available for sale investments | 130 | 24 | 338 | (209)
Comprehensive loss | $ (37,499) | $ (18,422) | $ (68,345) | $ (44,432)
Basic and diluted net loss per common share (in dollars per share) | $ (0.34) | $ (0.19) | $ (0.62) | $ (0.45)
Weighted average shares outstanding (in shares) | 110,338 | 98,787 | 110,253 | 98,690
Product [Member] |  |  |  |
Revenues: |  |  |  |
Revenues |  |  | $ 1,679 |
Royalty [Member] |  |  |  |
Revenues: |  |  |  |
Revenues | 696 | 142 | 3,018 | 3,803
Collaborative and Other Research and Development [Member] |  |  |  |
Revenues: |  |  |  |
Revenues | $ 752 | $ 12,352 | $ 2,638 | $ 12,667

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