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v3.19.2

Consolidated Statements of Cash Flows (Unaudited) - USD ($) $ in Thousands | 6 Months Ended
--- | ---
Jun. 30, 2019 | Jun. 30, 2018
Operating activities |  |
Net loss | $ (68,683) | $ (44,223)
Adjustments to reconcile net loss to net cash used in operating activities: |  |
Depreciation and amortization | 357 | 377
Stock-based compensation expense | 8,702 | 4,987
Amortization of debt issuance costs | 596 | 455
Amortization of premium/discount on investments | (17) | 140
Change in fair value of foreign currency derivative | 646 | 1,185
Changes in operating assets and liabilities: |  |
Receivables | 691 | 3,775
Inventory | 649 | (221)
Prepaid expenses and other assets | 84 | (347)
Deferred collaboration expense |  | 140
Accounts payable and accrued expenses | 2,579 | 4,447
Interest payable | 2,897 | 2,737
Deferred revenue |  | (7,000)
Net cash used in operating activities | (51,499) | (33,548)
Investing activities |  |
Acquisitions of property and equipment | (180) | (221)
Purchases of investments | (3,018) | (16,754)
Sales and maturities of investments | 41,357 | 34,435
Net cash provided by investing activities | 38,159 | 17,460
Financing activities |  |
Payment of senior credit facility |  | (3,450)
Proceeds from senior credit facility | 19,477 |
Net proceeds from common stock issued under stock-based compensation plans | 977 | 736
Increase in lease financing obligation |  | (37)
Net cash provided by (used in) financing activities | 20,454 | (2,751)
Increase (decrease) in cash, cash equivalents and restricted cash | 7,114 | (18,839)
Cash, cash equivalents and restricted cash at beginning of period | 28,275 | 53,568
Cash, cash equivalents and restricted cash at end of period | $ 35,389 | $ 34,729

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