    <SEC-DOCUMENT>0001171843-19-001171-index.html : 20190225
    <SEC-HEADER>0001171843-19-001171.hdr.sgml : 20190225
    <ACCEPTANCE-DATETIME>20190225091738
    ACCESSION NUMBER:		0001171843-19-001171
    CONFORMED SUBMISSION TYPE:	8-K
    PUBLIC DOCUMENT COUNT:		4
    CONFORMED PERIOD OF REPORT:	20190223
    ITEM INFORMATION:		Regulation FD Disclosure
    ITEM INFORMATION:		Financial Statements and Exhibits
    FILED AS OF DATE:		20190225
    DATE AS OF CHANGE:		20190225

    FILER:

    	COMPANY DATA:
    		COMPANY CONFORMED NAME:			BIOCRYST PHARMACEUTICALS INC
    		CENTRAL INDEX KEY:			0000882796
    		STANDARD INDUSTRIAL CLASSIFICATION:	BIOLOGICAL PRODUCTS (NO DIAGNOSTIC SUBSTANCES) [2836]
    		IRS NUMBER:				621413174
    		STATE OF INCORPORATION:			DE
    		FISCAL YEAR END:			1231

    	FILING VALUES:
    		FORM TYPE:		8-K
    		SEC ACT:		1934 Act
    		SEC FILE NUMBER:	000-23186
    		FILM NUMBER:		19628220

    	BUSINESS ADDRESS:
    		STREET 1:		4505 EMPEROR BOULEVARD
    		STREET 2:		SUITE 200
    		CITY:			DURHAM
    		STATE:			NC
    		ZIP:			27703
    		BUSINESS PHONE:		919-859-1302

    	MAIL ADDRESS:
    		STREET 1:		4505 EMPEROR BOULEVARD
    		STREET 2:		SUITE 200
    		CITY:			DURHAM
    		STATE:			NC
    		ZIP:			27703
    </SEC-HEADER>
    <DOCUMENT>
    <TYPE>8-K
    <SEQUENCE>1
    <FILENAME>f8k_022519.htm
    <DESCRIPTION>FORM 8-K
    <TEXT>
    Document 1 - file: f8k_022519.htm

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>EX-99.1
    <SEQUENCE>2
    <FILENAME>exh_991.htm
    <DESCRIPTION>PRESS RELEASE
    <TEXT>
    Document 2 - file: exh_991.htm

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>EX-99.2
    <SEQUENCE>3
    <FILENAME>exh_992.htm
    <DESCRIPTION>EXHIBIT 99.2
    <TEXT>
    Document 3 - file: exh_992.htm

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>4
    <FILENAME>poster.jpg
    <TEXT>
    Document 4 - file: poster.jpg

    </DOCUMENT>
    </SEC-DOCUMENT>