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Note 10 - Collaborative and Other Research and Development Contracts 1 (Details Textual) - USD ($) $ in Thousands |  |  |  |  |  | 1 Months Ended | 3 Months Ended | 12 Months Ended | 55 Months Ended | 57 Months Ended |  |
--- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | ---
Mar. 04, 2020 | Nov. 05, 2019 | Sep. 06, 2018 | Jun. 16, 2015 | Feb. 28, 2006 | Sep. 30, 2013 | Jun. 30, 2006 | Jun. 30, 2000 | Dec. 31, 2019 | Sep. 30, 2019 | Jun. 30, 2019 | Mar. 31, 2019 | Dec. 31, 2018 | Sep. 30, 2018 | Jun. 30, 2018 | Mar. 31, 2018 | Dec. 31, 2020 | Dec. 31, 2019 | Dec. 31, 2018 | Dec. 31, 2017 | Dec. 31, 2019 | Dec. 31, 2019 | Mar. 31, 2015 | Nov. 11, 2011
Revenue from Contract with Customer, Including Assessed Tax |  |  |  |  |  |  |  |  | $ 39,725 | $ 1,775 | $ 1,448 | $ 5,887 | $ 2,729 | $ 1,454 | $ 12,494 | $ 3,976 |  | $ 48,835 | $ 20,653 | $ 25,186 |  |  |  |
Arbitration Proceedings of SUL Agreement [Member] | Subsequent Event [Member] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Litigation Settlement, Amount Awarded from Other Party | $ 5,000 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
US Department of Health and Human Services [Member] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Collaborative Agreement Contract Value |  |  | $ 34,660 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Contract Term |  |  | 5 years |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Proceeds from Collaborators |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 13,864 |  |  |  |  |  |
US Department of Health and Human Services [Member] | Forecast [Member] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Proceeds from Collaborators |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | $ 6,932 |  |  |  |  |  |  |
Torii Pharmaceutical Co. [Member] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Upfront Payments Receivable Amount |  | $ 22,000 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Potential Milestone Payments Receivable if Regulatory Approval Before December 31, 2020 |  | 20,000 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Potential Milestone Payments Receivable if Regulatory Approval Before December 31, 2021 |  | $ 15,000 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Maximum Customary Reduction on Royalty Rate |  | 50.00% |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Royalty Payments Receivable, Expiration Term From First Commercial |  | 10 years |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Revenue from Contract with Customer, Including Assessed Tax |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 20,101 |  |  |  |  |  |
Torii Pharmaceutical Co. [Member] | License [Member] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Revenue from Contract with Customer, Including Assessed Tax |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 19,344 |  |  |  |  |  |
Torii Pharmaceutical Co. [Member] | Service [Member] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Revenue from Contract with Customer, Including Assessed Tax |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 757 |  |  |  |  |  |
Torii Pharmaceutical Co. [Member] | Minimum [Member] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Royalty Rate if Maintains Sakigake Designation |  | 20.00% |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Royalty Rate, Otherwise |  | 15.00% |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Torii Pharmaceutical Co. [Member] | Maximum [Member] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Royalty Rate if Maintains Sakigake Designation |  | 40.00% |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Royalty Rate, Otherwise |  | 35.00% |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
CSL Limited [Member |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Proceeds from License Fees Received |  |  |  | $ 33,740 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Milestone Payment Received |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | $ 12,000 |  |  |
Royalty Term |  |  |  | 10 years |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Base Contract [Member] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Government Contract Receivable |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | $ 16,265 |
Additional Development Options [Member] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Government Contract Receivable |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 22,855 |
ASPRBARDA Contract [Member] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Government Contract Receivable |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | $ 39,120 |
Proceeds from awards for Research and Development Contracts |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | $ 20,574 |  |
Green Cross Corporation [Member] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Proceeds from License Fees Received |  |  |  |  |  |  | $ 250 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Mundipharma [Member] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Upfront Payments Receivable Amount |  |  |  |  | $ 10,000 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Potential Milestone Payments Receivable |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | $ 15,000
AECOM and IRL [Member] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Milestone Payment Minimum |  |  |  |  |  |  |  | $ 1,400 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Milestone Payment Maximum |  |  |  |  |  |  |  | 4,000 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Annual License Fee Minimum |  |  |  |  |  |  |  | 150 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Annual License Fee Maximum |  |  |  |  |  |  |  | $ 500 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Advance Notice Period for Termination of Agreement |  |  |  |  |  |  |  | 60 days |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
National Institute of Allergy and Infectious Diseases [Member] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Collaborative Agreement Contract Value |  |  |  |  |  | $ 5,000 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Expected Receivable From Awards for Research and Development Contracts |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | $ 43,035 |  |  |  |  |  |
UAB [Member] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Period of Agreement |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 25 years |  |  |  |  |  |
Renewable Period of Agreement |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 5 years |  |  |  |  |  |

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