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Note 1 - Significant Accounting Policies (Tables)
6 Months Ended
Jun. 30, 2020
Notes Tables  
Debt Securities, Available-for-sale [Table Text Block]
   

June 30, 2020

 
   

Amortized

Cost

  

Accrued

Interest

  

Gross

Unrealized

Gains

  

Gross

Unrealized

Losses

  

Estimated

Fair Value

 

Obligations of the U.S. Government and its agencies

 $14,991  $-  $-  $-  $14,991 

Certificates of deposit

  938   3   3   -   944 

Total investments

 $15,929  $3  $3  $-  $15,935 
  

December 31, 2019

 
  

Amortized

Cost

  

Accrued

Interest

  

Gross

Unrealized

Gains

  

Gross

Unrealized

Losses

  

Estimated

Fair Value

 

Obligations of U.S. Government and its agencies

 $10,488  $50  $23  $-  $10,561 

Corporate debt securities

  9,742   59   10   (1

)

  9,810 

Certificates of deposit

  1,669   7   7   -   1,683 

Total investments

 $21,899  $116  $40  $(1

)

 $22,054 
Schedule of Receivables from Collaborations [Table Text Block]
      

June 30, 2020

     
  

Billed

  

Unbilled

  

Total

 

U.S. Department of Health and Human Services

 $19  $2,253  $2,272 

Shionogi & Co. Ltd.

  1,683   -   1,683 

Mundipharma International Holdings Limited

  35   -   35 

Seqirus UK Limited

  7   -   7 

Total receivables

 $1,744  $2,253  $3,997 
      

December 31, 2019

     
  

Billed

  

Unbilled

  

Total

 

U.S. Department of Health and Human Services

 $1,353  $15,023  $16,376 

Shionogi & Co. Ltd.

  1,336   4   1,340 

Green Cross Corporation

  2,924   8   2,932 

Mundipharma International Holdings Limited

  56   -   56 

Seqirus UK Limited

  1,091   351   1,442 

Total receivables

 $6,760  $15,386  $22,146 
Disaggregation of Revenue [Table Text Block]
  

Three Months

  

Six Months

 
  

2020

  

2019

  

2020

  

2019

 

Product sales

 $  $  $218  $1,679 

Royalty revenue

  44   696   1,989   3,018 

Collaborative and other research and development revenues:

                

U.S. Department of Health and Human Services

  2,545   752   4,152   2,638 

Torii Pharmaceutical Co., Ltd.

  282      1,335    

Total collaborative and other research and development revenues

  2,827   752   5,487   2,638 

Total revenues

 $2,871  $1,448  $7,694  $7,335