<SEC-DOCUMENT>0001127602-20-013457.txt : 20200408
<SEC-HEADER>0001127602-20-013457.hdr.sgml : 20200408
<ACCEPTANCE-DATETIME>20200408105151
ACCESSION NUMBER:		0001127602-20-013457
CONFORMED SUBMISSION TYPE:	3
PUBLIC DOCUMENT COUNT:		2
CONFORMED PERIOD OF REPORT:	20200329
FILED AS OF DATE:		20200408
DATE AS OF CHANGE:		20200408

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			Doyle Anthony
		CENTRAL INDEX KEY:			0001808688

	FILING VALUES:
		FORM TYPE:		3
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	000-23186
		FILM NUMBER:		20781397

	MAIL ADDRESS:	
		STREET 1:		4505 EMPEROR BLVD.
		STREET 2:		SUITE 200
		CITY:			DURHAM
		STATE:			NC
		ZIP:			27703

ISSUER:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			BIOCRYST PHARMACEUTICALS INC
		CENTRAL INDEX KEY:			0000882796
		STANDARD INDUSTRIAL CLASSIFICATION:	BIOLOGICAL PRODUCTS (NO DIAGNOSTIC SUBSTANCES) [2836]
		IRS NUMBER:				621413174
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	BUSINESS ADDRESS:	
		STREET 1:		4505 EMPEROR BOULEVARD
		STREET 2:		SUITE 200
		CITY:			DURHAM
		STATE:			NC
		ZIP:			27703
		BUSINESS PHONE:		919-859-1302

	MAIL ADDRESS:	
		STREET 1:		4505 EMPEROR BOULEVARD
		STREET 2:		SUITE 200
		CITY:			DURHAM
		STATE:			NC
		ZIP:			27703
</SEC-HEADER>
<DOCUMENT>
<TYPE>3
<SEQUENCE>1
<FILENAME>form3.xml
<DESCRIPTION>PRIMARY DOCUMENT
<TEXT>
<XML>
<?xml version="1.0"?>
<ownershipDocument>

    <schemaVersion>X0206</schemaVersion>

    <documentType>3</documentType>

    <periodOfReport>2020-03-29</periodOfReport>

    <noSecuritiesOwned>1</noSecuritiesOwned>

    <issuer>
        <issuerCik>0000882796</issuerCik>
        <issuerName>BIOCRYST PHARMACEUTICALS INC</issuerName>
        <issuerTradingSymbol>BCRX</issuerTradingSymbol>
    </issuer>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001808688</rptOwnerCik>
            <rptOwnerName>Doyle Anthony</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>4505 EMPEROR BLVD.</rptOwnerStreet1>
            <rptOwnerStreet2>SUITE 200</rptOwnerStreet2>
            <rptOwnerCity>DURHAM</rptOwnerCity>
            <rptOwnerState>NC</rptOwnerState>
            <rptOwnerZipCode>27703</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isOfficer>1</isOfficer>
            <officerTitle>Chief Financial Officer</officerTitle>
        </reportingOwnerRelationship>
    </reportingOwner>

    <footnotes></footnotes>

    <remarks>EXHIBIT LIST: EX-24 Power of Attorney</remarks>

    <ownerSignature>
        <signatureName>/s/ Alane P. Barnes, by power of attorney</signatureName>
        <signatureDate>2020-04-08</signatureDate>
    </ownerSignature>
</ownershipDocument>
</XML>
</TEXT>
</DOCUMENT>
<DOCUMENT>
<TYPE>EX-24
<SEQUENCE>2
<FILENAME>doc1.txt
<DESCRIPTION>POWER OF ATTORNEY (PUBLIC): EXHIBIT 24 - POWER OF ATTORNEY
<TEXT>
POWER OF ATTORNEY
March 31, 2020

      	The undersigned hereby constitutes and appoints each of Alane
P. Barnes and Michael L. Jones, the Senior Vice President & Chief Legal
Officer and the Executive Director, Finance & Principal Accounting
Officer, respectively, of BioCryst Pharmaceuticals, Inc. (the ?Company?),
signing singly and not jointly, with full power of substitution, as the
undersigned?s true and lawful attorney-in-fact to:

(1)	prepare, execute in the undersigned?s name and on the undersigned?s
behalf, and submit to the U.S. Securities and Exchange Commission (the
?SEC?) a Form ID, including amendments thereto (the ?Form ID?), and any
other documents necessary or appropriate to obtain codes and passwords
enabling the undersigned to make electronic filings with the SEC of
reports required by the Securities Exchange Act of 1934, as amended (the
?Exchange Act?), or any rule or regulation of the SEC;

(2)	prepare, execute in the undersigned?s name and on the undersigned?s
behalf, and submit to the SEC, any and all Forms 3, 4, and 5 (the
?Section 16 Filings?), including amendments thereto, required to be filed
under Section 16(a) of the Exchange Act and the rules thereunder with
respect to equity securities of the Company;

(3)	do and perform any and all acts for and on behalf of the
undersigned which may be necessary or desirable to complete and execute
such Form ID and any Section 16 Filings and to file such Form ID and any
Section 16 Filings with the SEC and any stock exchange or similar
authority; and

(4)	take any other action of any type whatsoever in connection with the
foregoing which, in the opinion of such attorney-in-fact, may be of
benefit to, in the best interest of, or legally required by, the
undersigned, it being understood that the documents executed by such
attorney-in-fact on behalf of the undersigned pursuant to this Power of
Attorney shall be in such form and shall contain such terms and
conditions as such attorney-in-fact may approve in such attorney-in-
fact's discretion.

      	The undersigned hereby grants to each such attorney-in-fact
full power and authority to do and perform any and every act and thing
whatsoever requisite, necessary, or proper to be done in the exercise of
any of the rights and powers herein granted, as fully to all intents and
purposes as the undersigned might or could do if personally present, with
full power of substitution or revocation, hereby ratifying and confirming
that each such attorney-in-fact, or such attorney-in-fact's substitute or
substitutes, shall lawfully do or cause to be done by virtue of this
power of attorney and the rights and powers herein granted.  The
undersigned hereby authorizes, approves, and ratifies any and all prior
actions taken by such attorneys-in-fact in connection with the matters
contemplated herein.  The undersigned acknowledges that such attorneys-
in-fact, in serving in such capacity at the request of the undersigned,
do not assume any of the undersigned's responsibilities to comply with
the Exchange Act or any rule or regulation of the SEC.

      	This Power of Attorney shall remain in full force and effect
until the undersigned is no longer required to file a Form ID, any
Section 16 Filings, or any amendments or changes thereto, with respect to
the undersigned?s holdings of and transactions in securities issued by
the Company, unless earlier revoked by the undersigned in a signed
writing delivered to the foregoing attorneys-in-fact.

      	IN WITNESS WHEREOF, the undersigned has caused this Power of
Attorney to be executed as of the date first written above.




	By:  	/s/ Anthony Doyle
	Name:  Anthony Doyle



</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
