<SEC-DOCUMENT>0001140361-20-009639-index.html : 20200424
<SEC-HEADER>0001140361-20-009639.hdr.sgml : 20200424
<ACCEPTANCE-DATETIME>20200424085535
ACCESSION NUMBER:		0001140361-20-009639
CONFORMED SUBMISSION TYPE:	S-3
PUBLIC DOCUMENT COUNT:		10
FILED AS OF DATE:		20200424
DATE AS OF CHANGE:		20200424

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			BIOCRYST PHARMACEUTICALS INC
		CENTRAL INDEX KEY:			0000882796
		STANDARD INDUSTRIAL CLASSIFICATION:	BIOLOGICAL PRODUCTS (NO DIAGNOSTIC SUBSTANCES) [2836]
		IRS NUMBER:				621413174
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		S-3
		SEC ACT:		1933 Act
		SEC FILE NUMBER:	333-237820
		FILM NUMBER:		20812670

	BUSINESS ADDRESS:	
		STREET 1:		4505 EMPEROR BOULEVARD
		STREET 2:		SUITE 200
		CITY:			DURHAM
		STATE:			NC
		ZIP:			27703
		BUSINESS PHONE:		919-859-1302

	MAIL ADDRESS:	
		STREET 1:		4505 EMPEROR BOULEVARD
		STREET 2:		SUITE 200
		CITY:			DURHAM
		STATE:			NC
		ZIP:			27703
</SEC-HEADER>
<DOCUMENT>
<TYPE>S-3
<SEQUENCE>1
<FILENAME>nt10011234x1_s3.htm
<DESCRIPTION>S-3
<TEXT>
Document 1 - file: nt10011234x1_s3.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-4.9
<SEQUENCE>2
<FILENAME>nt10011234x1_ex4-9.htm
<DESCRIPTION>EXHIBIT 4.9
<TEXT>
Document 2 - file: nt10011234x1_ex4-9.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-5.1
<SEQUENCE>3
<FILENAME>nt10011234x1_ex5-1.htm
<DESCRIPTION>EXHIBIT 5.1
<TEXT>
Document 3 - file: nt10011234x1_ex5-1.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-23.1
<SEQUENCE>4
<FILENAME>nt10011234x1_ex23-1.htm
<DESCRIPTION>EXHIBIT 23.1
<TEXT>
Document 4 - file: nt10011234x1_ex23-1.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-25.1
<SEQUENCE>5
<FILENAME>nt10011234x1_ex25-1.htm
<DESCRIPTION>EXHIBIT 25.1
<TEXT>
Document 5 - file: nt10011234x1_ex25-1.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>6
<FILENAME>logo_biocryst2a.jpg
<TEXT>
Document 6 - file: logo_biocryst2a.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>7
<FILENAME>logo_biocryst2ax1.jpg
<TEXT>
Document 7 - file: logo_biocryst2ax1.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>8
<FILENAME>nc10011234x1_ex5-1image1.jpg
<TEXT>
Document 8 - file: nc10011234x1_ex5-1image1.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>9
<FILENAME>nt10011234x1_ex25-1image01.jpg
<TEXT>
Document 9 - file: nt10011234x1_ex25-1image01.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>10
<FILENAME>nt10011234x1_ex25-1image02.jpg
<TEXT>
Document 10 - file: nt10011234x1_ex25-1image02.jpg

</DOCUMENT>
</SEC-DOCUMENT>