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v3.20.4

Consolidated Statements of Comprehensive Loss - USD ($) shares in Thousands, $ in Thousands | 12 Months Ended
--- | ---
Dec. 31, 2020 | Dec. 31, 2019 | Dec. 31, 2018
Revenues: |  |  |
Revenues | $ 17,812 | $ 48,835 | $ 20,653
Expenses |  |  |
Cost of products sold | 1,550 | 3,726 |
Research and development | 122,964 | 107,068 | 84,888
Selling, general and administrative | 67,929 | 37,121 | 29,514
Royalty | 126 | 375 | 471
Total operating expenses | 192,569 | 148,290 | 114,873
Loss from operations | (174,757) | (99,455) | (94,220)
Interest and other income | 9,420 | 1,933 | 2,252
Interest expense | (14,501) | (11,892) | (9,176)
Loss on extinguishment of debt | (2,011) |  |
Gain (loss) on foreign currency | (965) | 517 | (108)
Net loss | (182,814) | (108,897) | (101,252)
Unrealized gain (loss) on available for sale investments | (36) | 336 | (54)
Net comprehensive loss | $ (182,850) | $ (108,561) | $ (101,306)
Basic and diluted net loss per common share (in dollars per share) | $ (1.09) | $ (0.94) | $ (0.98)
Weighted average shares outstanding (in shares) | 167,267 | 115,600 | 103,185
Product [Member] |  |  |
Revenues: |  |  |
Revenues | $ 3,301 | $ 17,533 |
Royalty [Member] |  |  |
Revenues: |  |  |
Revenues | 3,381 | 6,303 | $ 6,101
Collaborative and Other Research and Development [Member] |  |  |
Revenues: |  |  |
Revenues | $ 11,130 | $ 24,999 | $ 14,552

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