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Note 3 - Royalty Monetizations (Details Textual) $ in Thousands |  |  | 12 Months Ended |  |
--- | --- | --- | --- | --- | ---
Dec. 07, 2020 USD ($) | Mar. 09, 2011 USD ($) | Dec. 31, 2020 USD ($) | Dec. 31, 2019 USD ($) | Dec. 31, 2018 USD ($) | Dec. 01, 2020 USD ($) | Nov. 30, 2020 ¥ / $
Proceeds from Issuance of Secured Debt |  |  | $ 119,867 |  |  |  |
Future Royalties Payable |  |  | 124,717 | $ 0 |  |  |
RPI 2019 Intermediate Finance Trust [Member] |  |  |  |  |  |  |
Future Royalties Payable |  |  | 125,000 |  |  |  |
RPI 2019 Intermediate Finance Trust [Member] | ORLADEYO [Member] |  |  |  |  |  |  |
Royalty Purchase Agreement, Royalties, Percentage of Sublicense Revenue in Other Markets | 20.00% |  |  |  |  |  |
RPI 2019 Intermediate Finance Trust [Member] | ORLADEYO [Member] | Annual Net Sales Under $350,000 [Member] |  |  |  |  |  |  |
Royalty Purchase Agreement, Royalties, Percentage of Annual Net Sales in Key Territories | 8.75% |  |  |  |  |  |
RPI 2019 Intermediate Finance Trust [Member] | ORLADEYO [Member] | Annual Net Sales Between $350,000 and $550,000 [Member] |  |  |  |  |  |  |
Royalty Purchase Agreement, Royalties, Percentage of Annual Net Sales in Key Territories | 2.75% |  |  |  |  |  |
RPI 2019 Intermediate Finance Trust [Member] | ORLADEYO [Member] | Annual Net Sales Over $550,000 [Member] |  |  |  |  |  |  |
Royalty Purchase Agreement, Royalties, Percentage of Annual Net Sales in Key Territories | 0.00% |  |  |  |  |  |
RPI 2019 Intermediate Finance Trust [Member] | ORLADEYO [Member] | Annual Net Sales Under $150,000 [Member] |  |  |  |  |  |  |
Royalty Purchase Agreement, Royalties, Percentage of Annual Net Sales in Other Markets | 20.00% |  |  |  |  |  |
RPI 2019 Intermediate Finance Trust [Member] | ORLADEYO [Member] | Annual Net Sales Between $150,000 and $230,000 [Member] |  |  |  |  |  |  |
Royalty Purchase Agreement, Royalties, Percentage of Annual Net Sales in Other Markets | 10.00% |  |  |  |  |  |
RPI 2019 Intermediate Finance Trust [Member] | ORLADEYO [Member] | Annual Net Sales Over $230,000 [Member] |  |  |  |  |  |  |
Royalty Purchase Agreement, Royalties, Percentage of Annual Net Sales in Other Markets | 0.00% |  |  |  |  |  |
RPI 2019 Intermediate Finance Trust [Member] | BCX9930 [Member] |  |  |  |  |  |  |
Royalty Purchase Agreement, Royalties, Percentage of Global Annual Net Sales | 1.00% |  |  |  |  |  |
RPI 2019 Intermediate Finance Trust [Member] | Future Royalties Payable [Member] |  |  |  |  |  |  |
Interest Payable |  |  | 2,108 |  |  |  |
Proceeds from Issuance of Debt | $ 125,000 |  |  |  |  |  |
Debt Issuance Costs, Net, Total |  |  | $ 2,370 |  |  |  |
Debt Instrument, Interest Rate, Effective Percentage |  |  | 24.00% |  |  |  |
Foreign Exchange Contract [Member] | Not Designated as Hedging Instrument [Member] |  |  |  |  |  |  |
Derivative, Loss on Derivative |  |  | $ 632 | 347 | $ 1,049 |  |
Derivative, Gain on Derivative |  |  | $ 662 | $ 863 | $ 941 |  |
PhaRMA Notes Member] | Currency Hedge Agreement [Member] |  |  |  |  |  |  |
Derivative, Forward Exchange Rate (in JPY per USD) | ¥ / $ |  |  |  |  |  |  | 100
JPR Royalty Sub LLC [Member] | PhaRMA Notes Member] |  |  |  |  |  |  |
Private Placement of Senior Secured Notes |  | $ 30,000 |  |  |  |  |
Debt Instrument, Interest Rate, Stated Percentage |  | 14.00% |  |  |  |  |
Secured Debt, Total |  |  |  |  |  | $ 30,000 |
Interest Payable |  |  |  |  |  | $ 20,614 |
Percentage of Carrying Amount in Excess of Fair Value |  |  |  | 3.00% |  |  |
JPR Royalty Sub LLC [Member] | PhaRMA Notes Member] | Fair Value, Inputs, Level 2 [Member] |  |  |  |  |  |  |
Notes Payable, Fair Value Disclosure |  |  |  | $ 30,000 |  |  |
JPR Royalty Sub LLC [Member] | Royalty Monetization [Member] |  |  |  |  |  |  |
Debt Instrument, Face Amount |  | $ 30,000 |  |  |  |  |
Proceeds from Issuance of Secured Debt |  | 22,691 |  |  |  |  |
Transaction Costs |  | 4,309 |  |  |  |  |
Interest Reserve |  | $ 3,000 |  |  |  |  |

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