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v3.21.2

Note 1 - Significant Accounting Policies (Details Textual) - USD ($) shares in Thousands, $ in Thousands | 3 Months Ended | 9 Months Ended |
--- | --- | --- | ---
Sep. 30, 2021 | Sep. 30, 2020 | Sep. 30, 2021 | Sep. 30, 2020 | Dec. 31, 2020
Restricted Cash and Cash Equivalents, Current, Total | $ 4,296 |  | $ 4,296 |  | $ 2,221
Investments, Total | 0 |  | 0 |  |
Reclassification from Accumulated Other Comprehensive Income, Current Period, before Tax |  |  | 1 | $ 1 |
Advertising Expense | 1,492 | $ 0 | 4,696 | 0 |
Interest Expense, Debt, Total | 14,115 | 2,927 | 40,514 | 8,892 |
Amortization of Debt Financing Costs and Original Issue Discounts | $ 158 | $ 381 | $ 369 | $ 1,061 |
Antidilutive Securities Excluded from Computation of Earnings Per Share, Amount (in shares) | 28,472 | 16,544 | 26,131 | 14,154 |
Foreign Exchange Contract [Member] | Not Designated as Hedging Instrument [Member] |  |  |  |  |
Derivative, Loss on Derivative |  |  |  | $ 630 |
Derivative, Gain on Derivative |  |  |  | 660 |
Computer Equipment [Member] |  |  |  |  |
Property, Plant and Equipment, Useful Life (Year) |  |  | 3 years |  |
Laboratory Equipment, Office Equipment and Software [Member] |  |  |  |  |
Property, Plant and Equipment, Useful Life (Year) |  |  | 5 years |  |
Furniture and Fixtures [Member] |  |  |  |  |
Property, Plant and Equipment, Useful Life (Year) |  |  | 7 years |  |
Trade Accounts Receivable [Member] |  |  |  |  |
Accounts Receivable, after Allowance for Credit Loss, Total | $ 0 |  | $ 0 |  | 0
Collaboration Receivables [Member] |  |  |  |  |
Accounts Receivable, Allowance for Credit Loss, Ending Balance | 0 |  | 0 |  | 0
ORLADEYO [Member] | Trade Accounts Receivable [Member] |  |  |  |  |
Accounts Receivable, after Allowance for Credit Loss, Total | 22,893 |  | 22,893 |  | 149
RAPIVAB [Member] | Trade Accounts Receivable [Member] |  |  |  |  |
Accounts Receivable, after Allowance for Credit Loss, Total | 33 |  | $ 33 |  | 254
Maximum [Member] |  |  |  |  |
Maturity Period of High Quality Marketable Securities (Year) |  |  | 3 years |  |
Average Maturity Period of High Quality Marketable Securities (Month) |  |  | 18 months |  |
Maturity Period of Short Term Investment (Month) |  |  | 12 months |  |
Average Maturity for Portfolio Investments (Month) |  |  | 18 months |  |
Minimum [Member] |  |  |  |  |
Long-term Investment Maturity, Minimum (Month) |  |  | 12 months |  |
Royalty Receivable [Member] |  |  |  |  |
Restricted Cash and Cash Equivalents, Current, Total | 2,872 |  | $ 2,872 |  | 796
Collateral for Credit [Member] |  |  |  |  |
Restricted Cash and Cash Equivalents, Current, Total | 1,424,000 |  | 1,424,000 |  | $ 1,425
Senior Credit Facility [Member] | MidCap Financial Services, LLC [Member] |  |  |  |  |
Line of Credit Facility, Remaining Borrowing Capacity | $ 75,000 |  | $ 75,000 |  |
Interest Expense, Debt, Total |  |  |  | $ 4,064 |

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