<SEC-DOCUMENT>0001140361-21-006664-index.html : 20210301
<SEC-HEADER>0001140361-21-006664.hdr.sgml : 20210301
<ACCEPTANCE-DATETIME>20210301163552
ACCESSION NUMBER:		0001140361-21-006664
CONFORMED SUBMISSION TYPE:	S-3ASR
PUBLIC DOCUMENT COUNT:		7
FILED AS OF DATE:		20210301
DATE AS OF CHANGE:		20210301
EFFECTIVENESS DATE:		20210301

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			BIOCRYST PHARMACEUTICALS INC
		CENTRAL INDEX KEY:			0000882796
		STANDARD INDUSTRIAL CLASSIFICATION:	BIOLOGICAL PRODUCTS (NO DIAGNOSTIC SUBSTANCES) [2836]
		IRS NUMBER:				621413174
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		S-3ASR
		SEC ACT:		1933 Act
		SEC FILE NUMBER:	333-253719
		FILM NUMBER:		21698452

	BUSINESS ADDRESS:	
		STREET 1:		4505 EMPEROR BOULEVARD
		STREET 2:		SUITE 200
		CITY:			DURHAM
		STATE:			NC
		ZIP:			27703
		BUSINESS PHONE:		919-859-1302

	MAIL ADDRESS:	
		STREET 1:		4505 EMPEROR BOULEVARD
		STREET 2:		SUITE 200
		CITY:			DURHAM
		STATE:			NC
		ZIP:			27703
</SEC-HEADER>
<DOCUMENT>
<TYPE>S-3ASR
<SEQUENCE>1
<FILENAME>nt10020928x1_s3asr.htm
<DESCRIPTION>FORM S-3ASR
<TEXT>
Document 1 - file: nt10020928x1_s3asr.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-5.1
<SEQUENCE>2
<FILENAME>nt10020928x1_ex5-1.htm
<DESCRIPTION>EXHIBIT 5.1
<TEXT>
Document 2 - file: nt10020928x1_ex5-1.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-23.1
<SEQUENCE>3
<FILENAME>nt10020928x1_ex23-1.htm
<DESCRIPTION>EXHIBIT 23.1
<TEXT>
Document 3 - file: nt10020928x1_ex23-1.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-25.1
<SEQUENCE>4
<FILENAME>nt10020928x1_ex25-1.htm
<DESCRIPTION>EXHIBIT 25.1
<TEXT>
Document 4 - file: nt10020928x1_ex25-1.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>5
<FILENAME>logo_biocryst2a.jpg
<TEXT>
Document 5 - file: logo_biocryst2a.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>6
<FILENAME>nt10020928x1_ex25-1img01.jpg
<TEXT>
Document 6 - file: nt10020928x1_ex25-1img01.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>7
<FILENAME>nt10020928x1_ex25-1img02.jpg
<TEXT>
Document 7 - file: nt10020928x1_ex25-1img02.jpg

</DOCUMENT>
</SEC-DOCUMENT>