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Note 15- Collaborative and Other Relationships (Details Textual) $ in Thousands |  |  |  |  |  |  |  | 1 Months Ended | 12 Months Ended | 70 Months Ended |
--- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | ---
Sep. 15, 2021 USD ($) | Sep. 01, 2021 USD ($) | Mar. 04, 2020 USD ($) | Nov. 05, 2019 USD ($) | Sep. 06, 2018 USD ($) | Jun. 16, 2015 USD ($) | Sep. 30, 2013 USD ($) | Aug. 31, 2020 USD ($) | Jun. 30, 2000 USD ($) | Dec. 31, 2021 USD ($) | Dec. 31, 2020 USD ($) | Dec. 31, 2019 USD ($) | Mar. 31, 2021 USD ($) | Mar. 31, 2015 USD ($)
Revenue from Contract with Customer, Including Assessed Tax |  |  |  |  |  |  |  |  |  | $ 157,170 | $ 17,812 | $ 48,835 |  |
Arbitration Proceedings of SUL Agreement [Member] |  |  |  |  |  |  |  |  |  |  |  |  |  |
Litigation Settlement, Amount Awarded from Other Party |  |  | $ 5,000 |  |  |  |  |  |  |  |  |  |  |
Arbitration Proceedings of SUL Agreement [Member] | Other Income [Member] |  |  |  |  |  |  |  |  |  |  |  |  |  |
Gain (Loss) Related to Litigation Settlement, Total |  |  |  |  |  |  |  |  |  |  | 8,893 |  |  |
Arbitration Proceedings of SUL Agreement [Member] | Selling, General and Administrative Expenses [Member] |  |  |  |  |  |  |  |  |  |  |  |  |  |
Legal Fees |  |  |  |  |  |  |  |  |  |  | 5,026 |  |  |
US Department of Health and Human Services [Member] |  |  |  |  |  |  |  |  |  |  |  |  |  |
Collaborative Agreement Contract Value |  |  |  |  | $ 34,660 |  |  |  |  |  |  |  |  |
Contract Term (Year) |  |  |  |  | 5 years |  |  |  |  |  |  |  |  |
US Department of Health and Human Services [Member] | RAPIVAB [Member] |  |  |  |  |  |  |  |  |  |  |  |  |  |
Maximum Number of Products, Doses |  |  |  |  | 50,000 |  |  |  |  |  |  |  |  |
Number of Product Delivered, Doses |  |  |  |  |  |  |  |  |  | 9,980 |  | 20,000 |  |
Proceeds from Collaborators |  |  |  |  |  |  |  |  |  | $ 6,918 |  | $ 13,900 |  |
Number of Additional Products, Doses |  | 10,000 |  |  |  |  |  |  |  |  |  |  |  |
Revenue from Contract with Customer, Including Assessed Tax |  | $ 6,900 |  |  |  |  |  |  |  |  |  |  |  |
Torii Pharmaceutical Co. [Member] |  |  |  |  |  |  |  |  |  |  |  |  |  |
Revenue from Contract with Customer, Including Assessed Tax |  |  |  | $ 22,000 |  |  |  |  |  |  |  |  |  |
Potential Milestone Payments Receivable if Regulatory Approval Before December 31, 2021 |  |  |  | $ 15,000 |  |  |  |  |  |  |  |  |  |
Maximum Customary Reduction on Royalty Rate |  |  |  | 50.00% |  |  |  |  |  |  |  |  |  |
Royalty Payments Receivable, Expiration Term From First Commercial (Year) |  |  |  | 10 years |  |  |  |  |  |  |  |  |  |
Contract with Customer, Liability, Revenue Recognized |  |  |  |  |  |  |  |  |  |  | $ 1,899 | $ 20,101 |  |
Torii Pharmaceutical Co. [Member] | Minimum [Member] |  |  |  |  |  |  |  |  |  |  |  |  |  |
Royalty Rate if Maintains Sakigake Designation |  |  |  | 20.00% |  |  |  |  |  |  |  |  |  |
Torii Pharmaceutical Co. [Member] | Maximum [Member] |  |  |  |  |  |  |  |  |  |  |  |  |  |
Royalty Rate if Maintains Sakigake Designation |  |  |  | 40.00% |  |  |  |  |  |  |  |  |  |
CSL Limited [Member |  |  |  |  |  |  |  |  |  |  |  |  |  |
Proceeds from License Fees Received |  |  |  |  |  | $ 33,740 |  |  |  |  |  |  |  |
Milestone Payment Received |  |  |  |  |  |  |  |  |  |  |  |  | $ 12,000 |
Base Contract [Member] |  |  |  |  |  |  |  |  |  |  |  |  |  |
Government Contract Receivable |  |  |  |  |  |  |  |  |  |  |  |  |  | $ 16,265
Additional Development Options [Member] |  |  |  |  |  |  |  |  |  |  |  |  |  |
Government Contract Receivable |  |  |  |  |  |  |  |  |  |  |  |  |  | 22,855
ASPRBARDA Contract [Member] |  |  |  |  |  |  |  |  |  |  |  |  |  |
Government Contract Receivable |  |  |  |  |  |  |  |  |  |  |  |  |  | $ 39,120
Proceeds from awards for Research and Development Contracts |  |  |  |  |  |  |  |  |  | $ 20,574 |  |  |  |
AECOM and IRL [Member] |  |  |  |  |  |  |  |  |  |  |  |  |  |
Milestone Payment Minimum |  |  |  |  |  |  |  |  | $ 1,400 |  |  |  |  |
Milestone Payment Maximum |  |  |  |  |  |  |  |  | 4,000 |  |  |  |  |
Annual License Fee Minimum |  |  |  |  |  |  |  |  | 150 |  |  |  |  |
Annual License Fee Maximum |  |  |  |  |  |  |  |  | $ 500 |  |  |  |  |
National Institute of Allergy and Infectious Diseases [Member] |  |  |  |  |  |  |  |  |  |  |  |  |  |
Expected Receivable From Awards for Research and Development Contracts | $ 47,315 |  |  |  |  |  | $ 45,931 |  |  |  |  |  |  |
Collaborative Agreement Contract, Covenant, Maximum Amount of Funding |  |  |  |  |  |  |  | $ 43,908 |  |  |  |  |  |
Collaborative Agreement Contract Value |  |  |  |  |  |  |  | $ 6,326 |  |  |  |  |  |
UAB [Member] |  |  |  |  |  |  |  |  |  |  |  |  |  |
Period of Agreement (Year) |  |  |  |  |  |  |  |  |  | 25 years |  |  |  |
Renewable Period of Agreement (Year) |  |  |  |  |  |  |  |  |  | 5 years |  |  |  |

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