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Royalty Monetizations (Tables) | 6 Months Ended
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Jun. 30, 2022
Advance Royalties [Abstract] |
Schedule of Royalty Financing Obligations | The following table shows the activity within the Royalty financing obligations account (in thousands) as well as the effective interest rate as of June 30, 2022:
| 2020 RPI Royalty Agreement |  | 2021 RPI Royalty Agreement |  | OMERS Royalty Agreement |  | Total
Balance as of December 31, 2021 | $ | 147,224 |  |  | $ | 153,377 |  |  | $ | 148,774 |  |  | $ | 449,375 |
Deferred financing costs | — |  |  | (34) |  |  | — |  |  | (34) |
Non-cash Interest expense on Royalty financing obligations | 10,165 |  |  | 6,327 |  |  | 3,157 |  |  | 19,649 |
Royalty revenues paid and payable | (4,385) |  |  | (380) |  |  | — |  |  | (4,765) |
Balance as of March 31, 2022 | $ | 153,004 |  |  | $ | 159,290 |  |  | $ | 151,931 |  |  | $ | 464,225 |
Non-cash Interest expense on Royalty financing obligations | 10,462 |  |  | 6,020 |  |  | 3,224 |  |  | 19,706 |
Royalty revenues paid and payable | (5,764) |  |  | (501) |  |  | — |  |  | (6,265) |
Balance as of June 30, 2022 | $ | 157,702 |  |  | $ | 164,809 |  |  | $ | 155,155 |  |  | $ | 477,666 |
Effective interest rate | 25.5 | % |  | 12.1 | % |  | 8.5 | % |  |

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