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Consolidated Statements of Comprehensive Loss - USD ($)
shares in Thousands, $ in Thousands
 3 Months Ended 6 Months Ended
Jun. 30, 2023
Jun. 30, 2022
Jun. 30, 2023
Jun. 30, 2022
Revenues        
Revenues $ 82,491 $ 65,532 $ 151,269 $ 115,455
Expenses:        
Cost of product sales 894 246 1,825 482
Research and development 51,247 61,990 99,635 127,350
Selling, general and administrative 50,997 38,017 98,864 72,299
Royalty 56 1 63 3
Total operating expenses 103,194 100,254 200,387 200,134
Loss from operations (20,703) (34,722) (49,118) (84,679)
Interest and other income 3,750 609 7,128 663
Interest expense (28,915) (24,022) (56,311) (47,859)
Foreign currency gains (losses), net 301 132 72 (45)
Loss on extinguishment of debt (29,019) 0 (29,019) 0
Loss before income taxes (74,586) (58,003) (127,248) (131,920)
Income tax expense 740 856 1,411 1,135
Net loss (75,326) (58,859) (128,659) (133,055)
Foreign currency translation adjustment 59 104 118 182
Unrealized gain (loss) on available for sale investments 46 (275) 546 (344)
Comprehensive loss $ (75,221) $ (59,030) $ (127,995) $ (133,217)
Basic net loss per common share (in usd per share) $ (0.40) $ (0.32) $ (0.68) $ (0.72)
Diluted net loss per common share (in usd per share) $ (0.40) $ (0.32) $ (0.68) $ (0.72)
Weighted average shares outstanding, basic (in shares) 189,118 185,605 188,815 185,253
Weighted average shares outstanding, diluted (in shares) 189,118 185,605 188,815 185,253