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Revenue (Details) - USD ($)
$ in Thousands
 3 Months Ended 6 Months Ended
Jun. 30, 2023
Jun. 30, 2022
Jun. 30, 2023
Jun. 30, 2022
Disaggregation of Revenue [Line Items]        
Revenues $ 82,491 $ 65,532 $ 151,269 $ 115,455
Product sales, net        
Disaggregation of Revenue [Line Items]        
Revenues 80,504 64,888 148,670 114,434
Product sales, net | U.S.        
Disaggregation of Revenue [Line Items]        
Revenues 72,817 58,702 133,666 102,637
Product sales, net | Outside of U.S.        
Disaggregation of Revenue [Line Items]        
Revenues 8,192 6,521 15,757 12,290
ORLADEYO        
Disaggregation of Revenue [Line Items]        
Revenues 81,009 65,223 149,423 114,927
Other revenues        
Disaggregation of Revenue [Line Items]        
Revenues $ 1,482 $ 309 $ 1,846 $ 528