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Collaborative and Other Relationships (Details)
$ in Thousands
3 Months Ended 6 Months Ended
Nov. 05, 2019
USD ($)
Jun. 30, 2023
USD ($)
Jun. 30, 2022
USD ($)
Jun. 30, 2023
USD ($)
dose
Jun. 30, 2022
USD ($)
Collaborative and Other Relationships [Line Items]          
Revenues   $ 82,491 $ 65,532 $ 151,269 $ 115,455
Torii Pharmaceutical Co.          
Collaborative and Other Relationships [Line Items]          
Revenues $ 22,000        
Potential milestone payments receivable if regulatory approval before specified date $ 15,000        
Maximum customary reduction on royalty rate 50.00%        
Royalty payments receivable, expiration term from first commercial (in years) 10 years        
Torii Pharmaceutical Co. | Minimum          
Collaborative and Other Relationships [Line Items]          
Royalty rate if maintains sakigake designation 20.00%        
Torii Pharmaceutical Co. | Maximum          
Collaborative and Other Relationships [Line Items]          
Royalty rate if maintains sakigake designation 40.00%        
U.S. Department of Health and Human Services, net          
Collaborative and Other Relationships [Line Items]          
Contract term (in years)       5 years  
U.S. Department of Health and Human Services, net | Outside of U.S.          
Collaborative and Other Relationships [Line Items]          
Maximum number of products, doses | dose       50,000  
Number of product delivered, doses | dose       49,980