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Condensed Consolidated Statements of Comprehensive Loss - USD ($)
shares in Thousands, $ in Thousands
 3 Months Ended 9 Months Ended
Sep. 30, 2023
Sep. 30, 2022
Sep. 30, 2023
Sep. 30, 2022
Revenues        
Revenues $ 86,742 $ 75,827 $ 238,011 $ 191,282
Expenses:        
Cost of product sales 1,099 3,543 2,924 4,025
Research and development 46,879 52,740 146,514 180,090
Selling, general and administrative 50,648 36,919 149,512 109,218
Royalty 37 70 100 73
Total operating expenses 98,663 93,272 299,050 293,406
Loss from operations (11,921) (17,445) (61,039) (102,124)
Interest and other income 4,184 1,760 11,312 2,423
Interest expense (27,345) (24,775) (83,656) (72,634)
Foreign currency losses, net (737) (538) (665) (583)
Loss on extinguishment of debt 0 0 (29,019) 0
Loss before income taxes (35,819) (40,998) (163,067) (172,918)
Income tax expense 330 1,522 1,741 2,657
Net loss (36,149) (42,520) (164,808) (175,575)
Foreign currency translation adjustment (185) 695 (67) 877
Unrealized gain (loss) on available for sale investments 295 (808) 841 (1,152)
Comprehensive loss $ (36,039) $ (42,633) $ (164,034) $ (175,850)
Basic net loss per common share (in usd per share) $ (0.19) $ (0.23) $ (0.87) $ (0.95)
Diluted net loss per common share (in usd per share) $ (0.19) $ (0.23) $ (0.87) $ (0.95)
Weighted average shares outstanding, basic (in shares) 189,644 186,180 189,095 185,566
Weighted average shares outstanding, diluted (in shares) 189,644 186,180 189,095 185,566