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Royalty Financing Obligations (Details) - USD ($) |  |  |  | 12 Months Ended |
--- | --- | --- | --- | --- | ---
Nov. 19, 2021 | Dec. 07, 2020 | Mar. 09, 2011 | Dec. 31, 2023 | Dec. 31, 2022 | Dec. 31, 2021 | Dec. 01, 2020
Royalties Monetizations [Line Items] |  |  |  |  |  |  |
(Loss) gain on extinguishment of debt |  |  |  | $ (29,019,000) | $ 0 | $ 55,838,000 |
RPI 2019 Intermediate Finance Trust |  |  |  |  |  |  |
Royalties Monetizations [Line Items] |  |  |  |  |  |  |
Shares issued, common stock, premium | $ 4,269,000 |  |  |  |  |  |
RPI 2019 Intermediate Finance Trust | ORLADEYO |  |  |  |  |  |  |
Royalties Monetizations [Line Items] |  |  |  |  |  |  |
Royalty purchase agreement, royalties, percentage of sublicense revenue in other markets |  | 20.00% |  |  |  |  |
RPI 2019 Intermediate Finance Trust | ORLADEYO | Annual Net Sales Under $350,000 |  |  |  |  |  |  |
Royalties Monetizations [Line Items] |  |  |  |  |  |  |
Royalty purchase agreement, royalties, percentage of annual net sales in key territories |  | 8.75% |  |  |  |  |
RPI 2019 Intermediate Finance Trust | ORLADEYO | Annual Net Sales Between $350,000 and $550,000 |  |  |  |  |  |  |
Royalties Monetizations [Line Items] |  |  |  |  |  |  |
Royalty purchase agreement, royalties, percentage of annual net sales in key territories |  | 2.75% |  |  |  |  |
RPI 2019 Intermediate Finance Trust | ORLADEYO | Annual Net Sales Over $550,000 |  |  |  |  |  |  |
Royalties Monetizations [Line Items] |  |  |  |  |  |  |
Royalty purchase agreement, royalties, percentage of annual net sales in key territories |  | 0.00% |  |  |  |  |
RPI 2019 Intermediate Finance Trust | ORLADEYO | Annual Net Sales Under $150,000 |  |  |  |  |  |  |
Royalties Monetizations [Line Items] |  |  |  |  |  |  |
Royalty purchase agreement, royalties, percentage of annual net sales in other markets |  | 20.00% |  |  |  |  |
RPI 2019 Intermediate Finance Trust | ORLADEYO | Annual Net Sales Between $150,000 and $230,000 |  |  |  |  |  |  |
Royalties Monetizations [Line Items] |  |  |  |  |  |  |
Royalty purchase agreement, royalties, percentage of annual net sales in other markets |  | 10.00% |  |  |  |  |
RPI 2019 Intermediate Finance Trust | ORLADEYO | Annual Net Sales Over $230,000 |  |  |  |  |  |  |
Royalties Monetizations [Line Items] |  |  |  |  |  |  |
Royalty purchase agreement, royalties, percentage of annual net sales in other markets |  | 0.00% |  |  |  |  |
RPI 2019 Intermediate Finance Trust | BCX9930 |  |  |  |  |  |  |
Royalties Monetizations [Line Items] |  |  |  |  |  |  |
Royalty purchase agreement, royalties, maximum tiered profit share percentage on permitted sales in other markets | 3.00% |  |  |  |  |  |
RPI 2019 Intermediate Finance Trust | BCX9930 | Annual Net Sales Over $3 Billions |  |  |  |  |  |  |
Royalties Monetizations [Line Items] |  |  |  |  |  |  |
Royalty purchase agreement, royalties, annual net sales payment threshold | $ 3,000,000,000 |  |  |  |  |  |
RPI 2019 Intermediate Finance Trust | Future Royalties Payable |  |  |  |  |  |  |
Royalties Monetizations [Line Items] |  |  |  |  |  |  |
Proceeds from issuance of debt |  | $ 125,000,000 |  |  |  |  |
Debt issuance costs, net, total |  |  |  | $ 8,532,000 | $ 8,532,000 |  |
RPI 2021 and 2020 Intermediate Finance Trust | Future Royalties Payable |  |  |  |  |  |  |
Royalties Monetizations [Line Items] |  |  |  |  |  |  |
Proceeds from issuance of debt | $ 150,000,000 |  |  |  |  |  |
The 2021 RPI Royalty Purchase Agreement | Annual Net Sales Under $350,000 |  |  |  |  |  |  |
Royalties Monetizations [Line Items] |  |  |  |  |  |  |
Royalty purchase agreement, royalties, percentage of annual net sales in key territories | 0.75% |  |  |  |  |  |
The 2021 RPI Royalty Purchase Agreement | Annual Net Sales Between $350,000 and $550,000 |  |  |  |  |  |  |
Royalties Monetizations [Line Items] |  |  |  |  |  |  |
Royalty purchase agreement, royalties, percentage of annual net sales in key territories | 1.75% |  |  |  |  |  |
Royalty purchase agreement, royalties, percentage of annual net sales in other markets | 0.00% |  |  |  |  |  |
The 2021 RPI Royalty Purchase Agreement | Annual Net Sales Under $150,000 |  |  |  |  |  |  |
Royalties Monetizations [Line Items] |  |  |  |  |  |  |
Royalty purchase agreement, royalties, percentage of sublicense revenue in other markets | 3.00% |  |  |  |  |  |
The 2021 RPI Royalty Purchase Agreement | Annual Net Sales Between $150,000 and $230,000 |  |  |  |  |  |  |
Royalties Monetizations [Line Items] |  |  |  |  |  |  |
Royalty purchase agreement, royalties, percentage of sublicense revenue in other markets | 2.00% |  |  |  |  |  |
The 2021 RPI Royalty Purchase Agreement | Annual Net Sales Over $230,000 |  |  |  |  |  |  |
Royalties Monetizations [Line Items] |  |  |  |  |  |  |
Royalty purchase agreement, royalties, percentage of annual net sales in other markets | 0.00% |  |  |  |  |  |
The 2021 RPI Royalty Purchase Agreement | BCX9930 | Annual Net Sales Under $1.5 Million |  |  |  |  |  |  |
Royalties Monetizations [Line Items] |  |  |  |  |  |  |
Royalty purchase agreement, royalties, percentage of annual net sales in key territories | 3.00% |  |  |  |  |  |
The 2021 RPI Royalty Purchase Agreement | BCX9930 | Annual Net Sales Between $1.5 And $3 Million |  |  |  |  |  |  |
Royalties Monetizations [Line Items] |  |  |  |  |  |  |
Royalty purchase agreement, royalties, percentage of annual net sales in key territories | 2.00% |  |  |  |  |  |
The 2021 RPI Royalty Purchase Agreement | BCX9930 | Annual Net Sales Over $3 Billions |  |  |  |  |  |  |
Royalties Monetizations [Line Items] |  |  |  |  |  |  |
Royalty purchase agreement, royalties, percentage of annual net sales in other markets | 0.00% |  |  |  |  |  |
OMERS Capital Markets | ORLADEYO |  |  |  |  |  |  |
Royalties Monetizations [Line Items] |  |  |  |  |  |  |
Royalty purchase agreement, royalties, percentage of sublicense revenue in other markets | 20.00% |  |  |  |  |  |
Royalty purchase agreement, royalties, percentage of annual net sales in other markets | 10.00% |  |  |  |  |  |
Royalty purchase agreement, royalties, percentage of purchase price | 155.00% |  |  |  |  |  |
Royalty purchase agreement, royalties, purchase price, amount | $ 150,000,000 |  |  |  |  |  |
OMERS Capital Markets | ORLADEYO | Annual Net Sales Under $350,000 |  |  |  |  |  |  |
Royalties Monetizations [Line Items] |  |  |  |  |  |  |
Royalty purchase agreement, royalties, percentage of annual net sales | 7.50% |  |  |  |  |  |
Royalty purchase agreement, royalties, percentage of annual net sales, based on reduction in sales | 10.00% |  |  |  |  |  |
OMERS Capital Markets | ORLADEYO | Annual Net Sales Between $350,000 and $550,000 |  |  |  |  |  |  |
Royalties Monetizations [Line Items] |  |  |  |  |  |  |
Royalty purchase agreement, royalties, percentage of annual net sales | 6.00% |  |  |  |  |  |
Royalty purchase agreement, royalties, percentage of annual net sales, based on reduction in sales | 3.00% |  |  |  |  |  |
OMERS Capital Markets | ORLADEYO | Annual Net Sales Over $550,000 |  |  |  |  |  |  |
Royalties Monetizations [Line Items] |  |  |  |  |  |  |
Royalty purchase agreement, royalties, percentage of annual net sales | 0.00% |  |  |  |  |  |
Royalty purchase agreement, royalties, percentage of annual net sales, based on reduction in sales | 0.00% |  |  |  |  |  |
OMERS Capital Markets | ORLADEYO | Annual Net Sales Under $150,000 |  |  |  |  |  |  |
Royalties Monetizations [Line Items] |  |  |  |  |  |  |
Royalty purchase agreement, royalties, percentage of sublicense revenue in other markets | 20.00% |  |  |  |  |  |
OMERS Capital Markets | ORLADEYO | Annual Net Sales Between $150,000 and $230,000 |  |  |  |  |  |  |
Royalties Monetizations [Line Items] |  |  |  |  |  |  |
Royalty purchase agreement, royalties, percentage of sublicense revenue in other markets | 10.00% |  |  |  |  |  |
OMERS Capital Markets | ORLADEYO | Annual Net Sales Over $230,000 |  |  |  |  |  |  |
Royalties Monetizations [Line Items] |  |  |  |  |  |  |
Royalty purchase agreement, royalties, percentage of sublicense revenue in other markets | 0.00% |  |  |  |  |  |
OMERS Royalty Agreement |  |  |  |  |  |  |
Royalties Monetizations [Line Items] |  |  |  |  |  |  |
Effective interest rate |  |  |  | 10.00% | 10.60% |  |
2020 RPI Royalty Agreement |  |  |  |  |  |  |
Royalties Monetizations [Line Items] |  |  |  |  |  |  |
Effective interest rate |  |  |  | 22.30% | 22.40% |  |
2021 RPI Royalty Agreement |  |  |  |  |  |  |
Royalties Monetizations [Line Items] |  |  |  |  |  |  |
Effective interest rate |  |  |  | 0.00% | 13.10% |  |
JPR Royalty Sub LLC | PhaRMA Notes |  |  |  |  |  |  |
Royalties Monetizations [Line Items] |  |  |  |  |  |  |
Private placement of senior secured notes |  |  | $ 30,000,000 |  |  |  |
Debt instrument, interest rate, stated percentage |  |  | 14.00% |  |  |  |
Secured debt, total |  |  |  |  |  |  | $ 30,000,000
Interest payable |  |  |  |  |  |  | $ 20,614,000
(Loss) gain on extinguishment of debt |  |  |  |  |  | 25,838,000 |
JPR Royalty Sub LLC | PhaRMA Notes | Fair Value, Inputs, Level 2 |  |  |  |  |  |  |
Royalties Monetizations [Line Items] |  |  |  |  |  |  |
Notes payable, fair value disclosure |  |  |  |  |  | $ 30,000,000 |
JPR Royalty Sub LLC | Royalty Monetization |  |  |  |  |  |  |
Royalties Monetizations [Line Items] |  |  |  |  |  |  |
Debt instrument, face amount |  |  | $ 30,000,000 |  |  |  |
Prepayment and repayment fees on Athyrium secured term loans |  |  | $ 22,691,000 |  |  |  |

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