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v3.24.0.1

Consolidated Statements of Cash Flows - USD ($) $ in Thousands | 12 Months Ended
--- | ---
Dec. 31, 2023 | Dec. 31, 2022 | Dec. 31, 2021
Cash flows from operating activities: |  |  |
Net loss | $ (226,539) | $ (247,116) | $ (184,062)
Adjustments to reconcile net loss to net cash used in operating activities: |  |  |
Depreciation and amortization | 1,655 | 1,437 | 777
Inventory obsolescence | 422 | 932 | 0
Stock-based compensation expense | 55,615 | 44,701 | 34,640
Non-cash interest expense on royalty financing obligations and secured term loan and amortization of debt issuance costs | 85,803 | 98,918 | 54,204
Amortization of premium/discount on investments | (10,263) | (1,777) | (2)
Loss (gain) on extinguishment of debt | 29,019 | 0 | (55,838)
Loss on impairment | 1,548 | 0 | 0
Changes in operating assets and liabilities: |  |  |
Receivables | (6,095) | (21,470) | (20,817)
Inventory | (1,450) | (12,423) | (8,767)
Prepaid expenses and other assets | (6,820) | (2,583) | (7,155)
Accounts payable and accrued expenses | (16,806) | (22,360) | 39,412
Interest payable | 0 | 0 | 4,168
Deferred revenue | (1,230) | (109) | 1,283
Net cash used in operating activities | (95,141) | (161,850) | (142,157)
Cash flows from investing activities: |  |  |
Acquisitions of property and equipment | (2,168) | (1,351) | (2,385)
Purchases of investments | (514,407) | (244,283) | (10,012)
Sales and maturities of investments | 385,077 | 117,396 | 28,201
Net cash (used in) provided by investing activities | (131,498) | (128,238) | 15,804
Cash flows from financing activities: |  |  |
Sale of common stock, net | 0 | 0 | 50,000
Net proceeds from common stock issued under stock-based compensation plans | 8,340 | 14,765 | 15,734
Net proceeds from common stock issued to directors in lieu of cash retainer | 342 | 190 | 60
Withholding taxes paid on stock-based awards | (2,172) | 0 | 0
Net proceeds from secured term loans | 300,000 | 73,072 | 0
Repayment of Athyrium secured term loans principal | (240,452) | 0 | 0
Prepayment and repayment fees on Athyrium secured term loans | (21,261) | 0 | 0
Payment of debt issuance costs on Pharmakon Tranche A term loan | (11,147) | 0 | 0
Principal payments on finance lease liabilities | (1,165) | 0 | 0
Net proceeds from royalty financing liabilities | 0 | 0 | 293,874
Net cash provided by financing activities | 32,485 | 88,027 | 359,668
Effects of exchange rates on cash, cash equivalents and restricted cash | 362 | 566 | 71
(Decrease) increase in cash, cash equivalents and restricted cash | (193,792) | (201,495) | 233,386
Cash, cash equivalents and restricted cash at beginning of year | 306,239 | 507,734 | 274,348
Cash, cash equivalents and restricted cash at end of year | 112,447 | 306,239 | 507,734
Supplemental cash flow disclosure: |  |  |
Cash paid for interest | 22,139 | 0 | 900
Cash paid for taxes | 1,434 | 3,542 | 118
Taxes withheld on stock-based awards included in accrued expenses | $ 4,199 | $ 1,990 | $ 984

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