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Condensed Consolidated Statements of Stockholders' Deficit - USD ($)
shares in Thousands, $ in Thousands
Total
Common Stock
Additional Paid-in Capital
Accumulated Other Comprehensive Income
Accumulated Deficit
Common stock, shares outstanding, beginning balance (in shares) at Dec. 31, 2022   187,906      
Beginning balance at Dec. 31, 2022 $ (294,597) $ 1,879 $ 1,158,118 $ 26 $ (1,454,620)
Increase (Decrease) in Stockholders' Equity [Roll Forward]          
Net loss (53,333)       (53,333)
Other comprehensive income (loss) 559     559  
Exercise of stock options, net (in shares)   702      
Exercise of stock options, net 3,502 $ 7 3,495    
Vesting of restricted stock units (in shares)   99      
Vesting of restricted stock units 0 $ 1 (1)    
Employee stock purchase plan sales, net (in shares)   176      
Employee stock purchase plan sales 1,575 $ 2 1,573    
Stock-based compensation expense 14,007   14,007    
Common stock, shares outstanding, ending balance (in shares) at Mar. 31, 2023   188,883      
Ending balance at Mar. 31, 2023 (328,287) $ 1,889 1,177,192 585 (1,507,953)
Common stock, shares outstanding, beginning balance (in shares) at Dec. 31, 2022   187,906      
Beginning balance at Dec. 31, 2022 (294,597) $ 1,879 1,158,118 26 (1,454,620)
Increase (Decrease) in Stockholders' Equity [Roll Forward]          
Net loss $ (164,808)        
Employee stock purchase plan sales, net (in shares) 338        
Common stock, shares outstanding, ending balance (in shares) at Sep. 30, 2023   189,803      
Ending balance at Sep. 30, 2023 $ (410,986) $ 1,898 1,205,744 800 (1,619,428)
Common stock, shares outstanding, beginning balance (in shares) at Mar. 31, 2023   188,883      
Beginning balance at Mar. 31, 2023 (328,287) $ 1,889 1,177,192 585 (1,507,953)
Increase (Decrease) in Stockholders' Equity [Roll Forward]          
Net loss (75,326)       (75,326)
Other comprehensive income (loss) 105     105  
Exercise of stock options, net (in shares)   401      
Exercise of stock options, net 1,748 $ 4 1,744    
Vesting of restricted stock units (in shares)   184      
Vesting of restricted stock units 0 $ 2 (2)    
Issuance of shares to directors in lieu of cash retainer (in shares)   23      
Issuance of shares to directors in lieu of cash retainer 206   206    
Stock-based compensation expense 12,841   12,841    
Common stock, shares outstanding, ending balance (in shares) at Jun. 30, 2023   189,491      
Ending balance at Jun. 30, 2023 (388,713) $ 1,895 1,191,981 690 (1,583,279)
Increase (Decrease) in Stockholders' Equity [Roll Forward]          
Net loss (36,149)       (36,149)
Other comprehensive income (loss) 110     110  
Exercise of stock options, net (in shares)   87      
Exercise of stock options, net 456 $ 1 455    
Vesting of restricted stock units (in shares)   60      
Employee stock purchase plan sales, net (in shares)   162      
Employee stock purchase plan sales 1,020 $ 2 1,018    
Issuance of shares to directors in lieu of cash retainer (in shares)   3      
Issuance of shares to directors in lieu of cash retainer 11   11    
Stock-based compensation expense 12,279   12,279    
Common stock, shares outstanding, ending balance (in shares) at Sep. 30, 2023   189,803      
Ending balance at Sep. 30, 2023 $ (410,986) $ 1,898 1,205,744 800 (1,619,428)
Common stock, shares outstanding, beginning balance (in shares) at Dec. 31, 2023 205,771 205,771      
Beginning balance at Dec. 31, 2023 $ (455,528) $ 2,058 1,222,236 1,337 (1,681,159)
Increase (Decrease) in Stockholders' Equity [Roll Forward]          
Net loss (35,379)       (35,379)
Other comprehensive income (loss) (566)     (566)  
Exercise of stock options, net (in shares)   176      
Exercise of stock options, net 552 $ 2 550    
Vesting of restricted stock units (in shares)   155      
Vesting of restricted stock units 0 $ 1 (1)    
Shares withheld for taxes for vesting of restricted stock units (in shares)   (8)      
Shares withheld for taxes for vesting of restricted stock units (38)   (38)    
Employee stock purchase plan sales, net (in shares)   251      
Employee stock purchase plan sales 1,129 $ 2 1,127    
Issuance of shares to directors in lieu of cash retainer (in shares)   2      
Issuance of shares to directors in lieu of cash retainer 11   11    
Stock-based compensation expense 13,652   13,652    
Common stock, shares outstanding, ending balance (in shares) at Mar. 31, 2024   206,347      
Ending balance at Mar. 31, 2024 $ (476,167) $ 2,063 1,237,537 771 (1,716,538)
Common stock, shares outstanding, beginning balance (in shares) at Dec. 31, 2023 205,771 205,771      
Beginning balance at Dec. 31, 2023 $ (455,528) $ 2,058 1,222,236 1,337 (1,681,159)
Increase (Decrease) in Stockholders' Equity [Roll Forward]          
Net loss $ (62,086)        
Employee stock purchase plan sales, net (in shares) 412        
Common stock, shares outstanding, ending balance (in shares) at Sep. 30, 2024 207,119 207,119      
Ending balance at Sep. 30, 2024 $ (468,563) $ 2,071 1,270,318 2,293 (1,743,245)
Common stock, shares outstanding, beginning balance (in shares) at Mar. 31, 2024   206,347      
Beginning balance at Mar. 31, 2024 (476,167) $ 2,063 1,237,537 771 (1,716,538)
Increase (Decrease) in Stockholders' Equity [Roll Forward]          
Net loss (12,674)       (12,674)
Other comprehensive income (loss) (214)     (214)  
Exercise of stock options, net (in shares)   80      
Exercise of stock options, net 264 $ 1 263    
Vesting of restricted stock units (in shares)   200      
Vesting of restricted stock units 0 $ 2 (2)    
Issuance of shares to directors in lieu of cash retainer (in shares)   2      
Issuance of shares to directors in lieu of cash retainer 12   12    
Stock-based compensation expense 13,173   13,173    
Common stock, shares outstanding, ending balance (in shares) at Jun. 30, 2024   206,629      
Ending balance at Jun. 30, 2024 (475,606) $ 2,066 1,250,983 557 (1,729,212)
Increase (Decrease) in Stockholders' Equity [Roll Forward]          
Net loss (14,033)       (14,033)
Other comprehensive income (loss) 1,736     1,736  
Exercise of stock options, net (in shares)   262      
Exercise of stock options, net 1,362 $ 3 1,359    
Vesting of restricted stock units (in shares)   66      
Vesting of restricted stock units 0 $ 1 (1)    
Employee stock purchase plan sales, net (in shares)   161      
Employee stock purchase plan sales 723 $ 1 722    
Issuance of shares to directors in lieu of cash retainer (in shares)   1      
Issuance of shares to directors in lieu of cash retainer 6   6    
Stock-based compensation expense $ 17,249   17,249    
Common stock, shares outstanding, ending balance (in shares) at Sep. 30, 2024 207,119 207,119      
Ending balance at Sep. 30, 2024 $ (468,563) $ 2,071 $ 1,270,318 $ 2,293 $ (1,743,245)