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Segment Information - Segment Reporting Information by Segment (Details) - USD ($)
$ in Thousands
 3 Months Ended
Mar. 31, 2025
Mar. 31, 2024
Segment Reporting Information [Line Items]    
Revenues $ 145,534 $ 92,761
Segment Reconciliation [Abstract]    
Cost of product sales 4,568 1,265
Research and development 37,270 46,493
Selling, general and administrative 82,469 59,491
Interest expense 23,494 24,506
Income tax expense 726 365
Net income (loss) 32 (35,379)
Reportable Segment    
Segment Reporting Information [Line Items]    
Revenues 145,534 92,761
Segment Reconciliation [Abstract]    
Cost of product sales 4,568 1,265
Selling, general and administrative 82,469 59,491
Interest income (3,024) (4,031)
Interest expense 23,494 24,506
Income tax expense 726 365
Net income (loss) 32 (35,379)
Adjustments and reconciling items 0 0
Royalty (1) 51
Reportable Segment | Berotralstat    
Segment Reconciliation [Abstract]    
Research and development 7,825 11,958
Reportable Segment | Factor D Program    
Segment Reconciliation [Abstract]    
Research and development 1,489 10,480
Reportable Segment | BCX17725    
Segment Reconciliation [Abstract]    
Research and development 7,308 7,759
Reportable Segment | Other research, preclinical and development costs    
Segment Reconciliation [Abstract]    
Research and development $ 20,648 $ 16,296