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v3.25.3

Significant Accounting Policies and Concentrations of Risk (Details) shares in Thousands | 3 Months Ended | 9 Months Ended |
--- | --- | --- | ---
Sep. 30, 2025 USD ($) | Sep. 30, 2024 | Sep. 30, 2025 USD ($) segment shares | Sep. 30, 2024 USD ($) shares | Dec. 31, 2024 USD ($)
Significant Accounting Policies and Concentration of Risk [Line Items] |  |  |  |  |
Number of reportable segments | segment |  |  | 1 |  |
Number of operating segments | segment |  |  | 1 |  |
Birmingham lease restricted cash | $ 1,979,000 |  | $ 1,979,000 |  | $ 1,610,000
Long-term investment maturity, minimum (in years) |  |  | 12 months |  |
Antidilutive securities excluded from computation of earnings per share, amount (in shares) | shares |  |  | 22,191 | 44,441 |
Reclassification from accumulated other comprehensive income, current period, before tax |  |  | $ 0 | $ 0 |
Revenue Benchmark | Product Concentration Risk | ORLADEYO |  |  |  |  |
Significant Accounting Policies and Concentration of Risk [Line Items] |  |  |  |  |
Revenue percentage | 88.00% | 88.00% | 86.00% | 88.00% |
Computer Equipment |  |  |  |  |
Significant Accounting Policies and Concentration of Risk [Line Items] |  |  |  |  |
Property, plant and equipment, useful life (in years) | 3 years |  | 3 years |  |
Laboratory Equipment, Office Equipment and Software |  |  |  |  |
Significant Accounting Policies and Concentration of Risk [Line Items] |  |  |  |  |
Property, plant and equipment, useful life (in years) | 5 years |  | 5 years |  |
Furniture and Fixtures |  |  |  |  |
Significant Accounting Policies and Concentration of Risk [Line Items] |  |  |  |  |
Property, plant and equipment, useful life (in years) | 5 years |  | 5 years |  |
Maximum |  |  |  |  |
Significant Accounting Policies and Concentration of Risk [Line Items] |  |  |  |  |
Maturity period of high quality marketable securities (in years) |  |  | 2 years |  |
Average maturity period of high quality marketable securities (in months) |  |  | 12 months |  |
Maturity period of short term investment (in months) |  |  | 12 months |  |
Collateral for Credit |  |  |  |  |
Significant Accounting Policies and Concentration of Risk [Line Items] |  |  |  |  |
Birmingham lease restricted cash | $ 1,400,000 |  | $ 1,400,000 |  | $ 1,400,000

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