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v3.25.3

Segment Information - Segment Reporting Information by Segment (Details) - USD ($) $ in Thousands | 3 Months Ended | 9 Months Ended
--- | --- | ---
Sep. 30, 2025 | Jun. 30, 2025 | Mar. 31, 2025 | Sep. 30, 2024 | Jun. 30, 2024 | Mar. 31, 2024 | Sep. 30, 2025 | Sep. 30, 2024
Segment Reporting Information [Line Items] |  |  |  |  |  |  |  |
Revenues | $ 159,395 |  |  | $ 117,085 |  |  | $ 468,282 | $ 319,178
Segment Reconciliation [Abstract] |  |  |  |  |  |  |  |
Cost of product sales | 2,187 |  |  | 3,211 |  |  | 9,553 | 6,175
Research and development | 44,603 |  |  | 41,081 |  |  | 125,259 | 125,197
Selling, general and administrative | 83,014 |  |  | 65,101 |  |  | 252,866 | 185,841
Interest expense | 19,661 |  |  | 24,828 |  |  | 64,737 | 74,067
Loss on extinguishment of debt | 2,740 |  |  | 0 |  |  | 6,911 | 0
Other income | 2,667 |  |  | 0 |  |  | 2,667 | 0
Income Tax Expense (Benefit) | (769) |  |  | 586 |  |  | 1,358 | 1,123
Net income (loss) | 12,899 | $ 5,085 | $ 32 | (14,033) | $ (12,674) | $ (35,379) | 18,016 | (62,086)
Reportable Segment |  |  |  |  |  |  |  |
Segment Reporting Information [Line Items] |  |  |  |  |  |  |  |
Revenues | 159,395 |  |  | 117,085 |  |  | 468,282 | 319,178
Segment Reconciliation [Abstract] |  |  |  |  |  |  |  |
Cost of product sales | 2,187 |  |  | 3,211 |  |  | 9,553 | 6,175
Selling, general and administrative | 83,014 |  |  | 65,101 |  |  | 252,866 | 185,841
Interest income | (2,238) |  |  | (3,591) |  |  | (7,778) | (11,176)
Interest expense | 19,661 |  |  | 24,828 |  |  | 64,737 | 74,067
Foreign currency (gains) losses, net | (35) |  |  | (98) |  |  | 27 | 37
Loss on extinguishment of debt | 2,740 |  |  | 0 |  |  | 6,911 | 0
Other income | 2,667 |  |  | 0 |  |  | 2,667 | 0
Income Tax Expense (Benefit) | (769) |  |  | 586 |  |  | 1,358 | 1,123
Net income (loss) | 12,899 |  |  | (14,033) |  |  | 18,016 | (62,086)
Adjustments and reconciling items | 0 |  |  | 0 |  |  | 0 | 0
Reportable Segment | Berotralstat |  |  |  |  |  |  |  |
Segment Reconciliation [Abstract] |  |  |  |  |  |  |  |
Research and development | 2,575 |  |  | 2,954 |  |  | 9,214 | 10,504
Reportable Segment | BCX17725 |  |  |  |  |  |  |  |
Segment Reconciliation [Abstract] |  |  |  |  |  |  |  |
Research and development | 7,574 |  |  | 1,154 |  |  | 13,346 | 6,591
Reportable Segment | Avoralstat |  |  |  |  |  |  |  |
Segment Reconciliation [Abstract] |  |  |  |  |  |  |  |
Research and development | 1,800 |  |  | 2,104 |  |  | 7,584 | 4,960
Reportable Segment | Factor D Program |  |  |  |  |  |  |  |
Segment Reconciliation [Abstract] |  |  |  |  |  |  |  |
Research and development | 35 |  |  | 1,193 |  |  | 454 | 7,299
Reportable Segment | Research, discovery and preclinical programs |  |  |  |  |  |  |  |
Segment Reconciliation [Abstract] |  |  |  |  |  |  |  |
Research and development | 5,457 |  |  | 3,309 |  |  | 11,641 | 8,325
Reportable Segment | Compensation and related personnel costs |  |  |  |  |  |  |  |
Segment Reconciliation [Abstract] |  |  |  |  |  |  |  |
Research and development | 13,313 |  |  | 14,257 |  |  | 38,025 | 42,630
Reportable Segment | Stock-based compensation |  |  |  |  |  |  |  |
Segment Reconciliation [Abstract] |  |  |  |  |  |  |  |
Research and development | 6,520 |  |  | 8,530 |  |  | 24,374 | 20,923
Reportable Segment | Other non-program specific and indirect costs |  |  |  |  |  |  |  |
Segment Reconciliation [Abstract] |  |  |  |  |  |  |  |
Research and development | $ 7,329 |  |  | $ 7,580 |  |  | $ 20,621 | $ 23,965

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